TY - JOUR
T1 - Background parenchymal enhancement in breast magnetic resonance imaging
T2 - A review of current evidences and future trends
AU - Rella, R.
AU - Bufi, E.
AU - Belli, P.
AU - Contegiacomo, A.
AU - Giuliani, M.
AU - Rosignuolo, M.
AU - Rinaldi, P.
AU - Manfredi, R.
PY - 2018/12/1
Y1 - 2018/12/1
N2 - Background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) is a dynamic process, which varies among women and within the same woman over time due to different factors. BPE has profound implications for women with or at risk of breast cancer. Breast radiologist should be aware of factors that could potentially influence BPE and have to be familiar with its typical appearance. Marked BPE could indeed affect the diagnostic accuracy of breast MRI, but this shortcoming can be minimized through evaluation by dedicated radiologists, in order to correctly interpret and properly manage the additional findings. BPE shows promise as an imaging biomarker but many issues need to be addressed before it can be used either to determine screening strategy or the value of risk-reducing interventions. This review analyzes the clinical influence of BPE on breast MRI interpretation, breast cancer staging and surgical outcome and discusses current available evidences about BPE as an imaging biomarker.
AB - Background parenchymal enhancement (BPE) on breast magnetic resonance imaging (MRI) is a dynamic process, which varies among women and within the same woman over time due to different factors. BPE has profound implications for women with or at risk of breast cancer. Breast radiologist should be aware of factors that could potentially influence BPE and have to be familiar with its typical appearance. Marked BPE could indeed affect the diagnostic accuracy of breast MRI, but this shortcoming can be minimized through evaluation by dedicated radiologists, in order to correctly interpret and properly manage the additional findings. BPE shows promise as an imaging biomarker but many issues need to be addressed before it can be used either to determine screening strategy or the value of risk-reducing interventions. This review analyzes the clinical influence of BPE on breast MRI interpretation, breast cancer staging and surgical outcome and discusses current available evidences about BPE as an imaging biomarker.
KW - Background parenchymal enhancement
KW - Breast cancer
KW - Imaging biomarker
KW - Magnetic resonance imaging (MRI)
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U2 - 10.1016/j.diii.2018.08.011
DO - 10.1016/j.diii.2018.08.011
M3 - Short survey
C2 - 30249463
AN - SCOPUS:85053666626
VL - 99
SP - 815
EP - 826
JO - Diagnostic and interventional imaging
JF - Diagnostic and interventional imaging
SN - 2211-5706
IS - 12
ER -