Bacterial genomic epidemiology, from local outbreak characterization to species-history reconstruction

Stefano Gaiarsa, Leone De Marco, Francesco Comandatore, Piero Marone, Claudio Bandi, Davide Sassera

Research output: Contribution to journalArticle

Abstract

Bacteriology has embraced the next-generation sequencing revolution, swiftly moving from the time of single genome sequencing to the age of genomic epidemiology. Hundreds and now even thousands of genomes are being sequenced for single bacterial species, allowing unprecedented levels of resolution and insight in the evolution and epidemic diffusion of the main bacterial pathogens. Here, we present a review of some of the most recent and groundbreaking studies in this field.

Original languageEnglish
Pages (from-to)319-327
Number of pages9
JournalPathogens and Global Health
Volume109
Issue number7
DOIs
Publication statusPublished - Oct 1 2015

Keywords

  • Bacteria
  • Carbapenem-resistant enterobacteriaceae
  • Genomic epidemiology
  • Mycobacterium tuberculosis
  • Next-generation sequencing
  • Salmonella typhi
  • Staphylococcus aureus
  • Streptococcus pneumoniae

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • Microbiology

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