Bacterial vaginosis and preterm delivery: An open question

Francesco De Seta, Andrea Sartore, Monica Piccoli, Gianpaolo Maso, Sandro Zicari, Francesca Panerari, Secondo Guaschino

Research output: Contribution to journalArticlepeer-review


OBJECTIVE: To evaluate the prevalence of bacterial vaginosis in a population of Italian pregnant women and to study its association with adverse pregnancy outcomes, particularly preterm delivery. STUDY DESIGN: After giving informed consent, 598 women were consecutively enrolled at their first prenatal visit (13-18 weeks of gestation). The presence of bacterial vaginosis was assessed by Gram's method at 13-18 weeks of gestation (early bacterial vaginosis) and at 28-32 weeks of gestation (late bacterial vaginosis). Univariate and multiple logistic regression models of analysis were used to assess the statistical significance of the data. RESULTS: Preterm delivery occurred in 14.7% of pregnant women positive for bacterial vaginosis at their first prenatal visit and in 6.9% of healthy women (OR 1.6, CI 1.07-2.51). In patients with bacterial vaginosis, preterm delivery occurred more often in the 36th week of gestation (78.6%). CONCLUSION: The presence of bacterial vaginosis at an early gestational age is associated with preterm delivery, although in the study population the condition did not seem to be related to great prematurity.

Original languageEnglish
Pages (from-to)313-318
Number of pages6
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Issue number5
Publication statusPublished - May 2005


  • Bacterial vaginosis
  • Delivery
  • Labor complications

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine


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