Abstract
In this study we evaluated the antibacterial activity of mastic gum, a resin obtained from the Pistacia lentiscus tree, against clinical isolates of Helicobacter pylori. The minimal bactericidal concentrations (MBCs) were obtained by a microdilution assay. Mastic gum killed 50% of the strains tested at a concentration of 125 μg/ml and 90% at a concentration of 500 μg/ml. The influence of sub-MBCs of mastic gum on the morphologies of H. pylori was evaluated by transmission electron microscopy. The lentiscus resin induced blebbing, morphological abnormalities and cellular fragmentation in H. pylori cells.
| Original language | English |
|---|---|
| Pages (from-to) | 611-614 |
| Number of pages | 4 |
| Journal | Journal of Chemotherapy |
| Volume | 13 |
| Issue number | 6 |
| Publication status | Published - 2001 |
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Keywords
- Antibacterial activity
- Electron microscopy
- Helicobacter pylori
- Mastic gum
- Pistacia lentiscus
ASJC Scopus subject areas
- Pharmacology (medical)
- Microbiology (medical)
Cite this
Bactericidal activity of Pistacia lentiscus mastic gum against Helicobacter pylori. / Marone, Piero; Bono, L.; Leone, E.; Bona, S.; Carretto, E.; Perversi, L.
In: Journal of Chemotherapy, Vol. 13, No. 6, 2001, p. 611-614.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bactericidal activity of Pistacia lentiscus mastic gum against Helicobacter pylori
AU - Marone, Piero
AU - Bono, L.
AU - Leone, E.
AU - Bona, S.
AU - Carretto, E.
AU - Perversi, L.
PY - 2001
Y1 - 2001
N2 - In this study we evaluated the antibacterial activity of mastic gum, a resin obtained from the Pistacia lentiscus tree, against clinical isolates of Helicobacter pylori. The minimal bactericidal concentrations (MBCs) were obtained by a microdilution assay. Mastic gum killed 50% of the strains tested at a concentration of 125 μg/ml and 90% at a concentration of 500 μg/ml. The influence of sub-MBCs of mastic gum on the morphologies of H. pylori was evaluated by transmission electron microscopy. The lentiscus resin induced blebbing, morphological abnormalities and cellular fragmentation in H. pylori cells.
AB - In this study we evaluated the antibacterial activity of mastic gum, a resin obtained from the Pistacia lentiscus tree, against clinical isolates of Helicobacter pylori. The minimal bactericidal concentrations (MBCs) were obtained by a microdilution assay. Mastic gum killed 50% of the strains tested at a concentration of 125 μg/ml and 90% at a concentration of 500 μg/ml. The influence of sub-MBCs of mastic gum on the morphologies of H. pylori was evaluated by transmission electron microscopy. The lentiscus resin induced blebbing, morphological abnormalities and cellular fragmentation in H. pylori cells.
KW - Antibacterial activity
KW - Electron microscopy
KW - Helicobacter pylori
KW - Mastic gum
KW - Pistacia lentiscus
UR - http://www.scopus.com/inward/record.url?scp=0035696437&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035696437&partnerID=8YFLogxK
M3 - Article
VL - 13
SP - 611
EP - 614
JO - Journal of Chemotherapy
JF - Journal of Chemotherapy
SN - 1120-009X
IS - 6
ER -