Abstract
In this study we evaluated the antibacterial activity of mastic gum, a resin obtained from the Pistacia lentiscus tree, against clinical isolates of Helicobacter pylori. The minimal bactericidal concentrations (MBCs) were obtained by a microdilution assay. Mastic gum killed 50% of the strains tested at a concentration of 125 μg/ml and 90% at a concentration of 500 μg/ml. The influence of sub-MBCs of mastic gum on the morphologies of H. pylori was evaluated by transmission electron microscopy. The lentiscus resin induced blebbing, morphological abnormalities and cellular fragmentation in H. pylori cells.
| Original language | English |
|---|---|
| Pages (from-to) | 611-614 |
| Number of pages | 4 |
| Journal | Journal of Chemotherapy |
| Volume | 13 |
| Issue number | 6 |
| Publication status | Published - 2001 |
Keywords
- Antibacterial activity
- Electron microscopy
- Helicobacter pylori
- Mastic gum
- Pistacia lentiscus
ASJC Scopus subject areas
- Pharmacology (medical)
- Microbiology (medical)