Abstract
In this study we evaluated the antibacterial activity of mastic gum, a resin obtained from the Pistacia lentiscus tree, against clinical isolates of Helicobacter pylori. The minimal bactericidal concentrations (MBCs) were obtained by a microdilution assay. Mastic gum killed 50% of the strains tested at a concentration of 125 μg/ml and 90% at a concentration of 500 μg/ml. The influence of sub-MBCs of mastic gum on the morphologies of H. pylori was evaluated by transmission electron microscopy. The lentiscus resin induced blebbing, morphological abnormalities and cellular fragmentation in H. pylori cells.
Original language | English |
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Pages (from-to) | 611-614 |
Number of pages | 4 |
Journal | Journal of Chemotherapy |
Volume | 13 |
Issue number | 6 |
Publication status | Published - 2001 |
Keywords
- Antibacterial activity
- Electron microscopy
- Helicobacter pylori
- Mastic gum
- Pistacia lentiscus
ASJC Scopus subject areas
- Pharmacology (medical)
- Microbiology (medical)