Balance function in patients with Williams syndrome

Stefania Barozzi, Daniela Soi, Chiara Gagliardi, Angelo Selicorni, Maria Francesca Bedeschi, Stella Forti, Federica Di Berardino, Antonio Cesarani, Daniele Brambilla

Research output: Contribution to journalArticle

Abstract

Impaired control of balance has been described in Williams syndrome (WS). The aim of this study was to investigate balance function by means of clinical and instrumental tests in order to measure postural sway in people with WS in an objective way. 23 WS patients (11 males, 12 females, mean age 17.52 ± 8.33 years) and 23 healthy subjects (11 males, 12 females, mean age 17.74 ± 8.93 years) performed static posturography with eyes open and closed, on a firm surface and on foam pads. The WS patients had higher mean length, velocity and surface values than controls under all of the test conditions, and their length and surface values were significantly higher in the eyes open test. The cognitive abilities of the WS patients were not related to their stabilometric performance. The greatest differences between the WS patients and the controls were found mainly in the older subjects. WS patients are more unstable than healthy subjects of the same age, particularly when they use visual information to maintain their balance: i.e. under conditions of normal everyday life. Possible explanations may be the ophthalmologic problems and the visuospatial difficulties attributed to a neural processing abnormality involving the dorsal stream impairment model. The balance function of WS patients is different from that of normal developing subjects, especially after adolescence when postural control is generally complete. This suggests an atypical developmental trajectory.

Original languageEnglish
Pages (from-to)221-225
Number of pages5
JournalGait and Posture
Volume38
Issue number2
DOIs
Publication statusPublished - Jun 2013

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Williams Syndrome
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Keywords

  • Balance
  • Static posturography
  • Williams syndrome

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Rehabilitation
  • Biophysics

Cite this

Barozzi, S., Soi, D., Gagliardi, C., Selicorni, A., Bedeschi, M. F., Forti, S., ... Brambilla, D. (2013). Balance function in patients with Williams syndrome. Gait and Posture, 38(2), 221-225. https://doi.org/10.1016/j.gaitpost.2012.11.012

Balance function in patients with Williams syndrome. / Barozzi, Stefania; Soi, Daniela; Gagliardi, Chiara; Selicorni, Angelo; Bedeschi, Maria Francesca; Forti, Stella; Di Berardino, Federica; Cesarani, Antonio; Brambilla, Daniele.

In: Gait and Posture, Vol. 38, No. 2, 06.2013, p. 221-225.

Research output: Contribution to journalArticle

Barozzi, S, Soi, D, Gagliardi, C, Selicorni, A, Bedeschi, MF, Forti, S, Di Berardino, F, Cesarani, A & Brambilla, D 2013, 'Balance function in patients with Williams syndrome', Gait and Posture, vol. 38, no. 2, pp. 221-225. https://doi.org/10.1016/j.gaitpost.2012.11.012
Barozzi S, Soi D, Gagliardi C, Selicorni A, Bedeschi MF, Forti S et al. Balance function in patients with Williams syndrome. Gait and Posture. 2013 Jun;38(2):221-225. https://doi.org/10.1016/j.gaitpost.2012.11.012
Barozzi, Stefania ; Soi, Daniela ; Gagliardi, Chiara ; Selicorni, Angelo ; Bedeschi, Maria Francesca ; Forti, Stella ; Di Berardino, Federica ; Cesarani, Antonio ; Brambilla, Daniele. / Balance function in patients with Williams syndrome. In: Gait and Posture. 2013 ; Vol. 38, No. 2. pp. 221-225.
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