Baroreflex and metaboreflex control of cardiovascular system during exercise in space

Massimo Pagani, Paolo Pizzinelli, Silvia Beltrami, Michele Massaro, Daniela Lucini, Ferdinando Iellamo

Research output: Contribution to journalArticle


This brief review summarizes current knowledge on the neural mechanisms of cardiovascular regulation during exercise in space, with specific emphasis on the role of the arterial baroreflex and the muscle metaboreflex, with the attendant modifications in autonomic nervous system activity, in determining the cardiovascular responses to exercise in microgravity conditions. Available data suggest that the muscle metaboreflex is enhanced during dynamic exercise in space and that the potentiation of the muscle metaboreflex affects the vagally mediated arterial baroreflex contribution to HR control.

Original languageEnglish
JournalRespiratory Physiology and Neurobiology
Issue numberSUPPL.
Publication statusPublished - Oct 2009


  • Arterial baroreflex
  • Cardiovascular responses
  • Exercise
  • Muscle metaboreflex
  • Space

ASJC Scopus subject areas

  • Physiology
  • Pulmonary and Respiratory Medicine
  • Neuroscience(all)
  • Medicine(all)

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