Baroreflex contribution to linear and nonlinear blood pressure and heart rate coupling in daily life: An assessment by cross mutual information

Marco Di Rienzo, P. Castiglioni, G. Parati, U. Zwiener, B. Pompe, D. Hoyer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A new procedure has been developed to 1) investigate the coupling between arterial blood pressure and heart rate variability in daily life and 2) identify the baroreflex contribution to such a coupling. The algorithm is based on the estimation of the Cross-Mutual Information (CMI) between systolic blood pressure (SBP) and RR-Interval (RRI) beat-to-beat values. CMI has been selected because of its capability to quantify both linear and nonlinear components of the coupling between variables. This procedure has been used to analyze data recorded in spontaneously behaving cats before and seven days after the surgical opening of the baroreflex loop as obtained by a sino-aortic denervation. Use of CMI indicates that over a time scale in the order of minutes the arterial baroreflex is the major determinant of the SBI-RRI link, accounting for about 2/3 of the total (linear and nonlinear) coupling measured between these variables.

Original languageEnglish
Title of host publicationComputers in Cardiology
EditorsA. Murray
Pages57-60
Number of pages4
Volume29
Publication statusPublished - 2002
EventComputers in Cardiology 2002 - Memphis, TN, United States
Duration: Sep 22 2002Sep 25 2002

Other

OtherComputers in Cardiology 2002
CountryUnited States
CityMemphis, TN
Period9/22/029/25/02

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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