Baroreflex sensitivity in cardiac patients with Chronic Congestive Heart Failure: Towards a non invasive assessment method

R. Colombo, G. Mazzuero, P. Lanfranchi, G. Spinatonda, P. Giannuzzi, G. Minuco

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Spectral analysis of RR interval and systolic arterial pressure variability was applied for the non invasive assessment of the baroreflex gain in Congestive Chronic Heart Failure (CHF). Forty-nine CHF patients were studied during rest, controlled breathing and head-up tilt. The alpha index, a non invasive measure of the overall gain of the RR to systolic arterial pressure (SAP) relationship, and a modified version called beta, incorporating the weighted coherence function, were computed in the low (LF) and high (HF) frequency bands by spectral analysis, and compared with the phenylephrine test slope. A linear model fitted on the beta index values during rest and controlled breathing showed a high correlation (r = 0.93, standard error of the estimation = 2.5 ms/mmHg) with the phenylephrine test slope. In severe CHF patients the beta index proposed, evaluated during rest and controlled breathing, may improve the baroreflex gain estimation and provide a non invasive assessment method that might be useful in gauging prognosis.

Original languageEnglish
Title of host publicationComputers in Cardiology
PublisherIEEE Comp Soc
Pages203-206
Number of pages4
Publication statusPublished - 1997
EventProceedings of the 1997 24th Annual Meeting on Computers in Cardiology - Lund, Sweden
Duration: Sep 7 1997Sep 10 1997

Other

OtherProceedings of the 1997 24th Annual Meeting on Computers in Cardiology
CityLund, Sweden
Period9/7/979/10/97

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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