Abstract
Spectral analysis of RR interval and systolic arterial pressure variability was applied for the non invasive assessment of the baroreflex gain in Congestive Chronic Heart Failure (CHF). Forty-nine CHF patients were studied during rest, controlled breathing and head-up tilt. The alpha index, a non invasive measure of the overall gain of the RR to systolic arterial pressure (SAP) relationship, and a modified version called beta, incorporating the weighted coherence function, were computed in the low (LF) and high (HF) frequency bands by spectral analysis, and compared with the phenylephrine test slope. A linear model fitted on the beta index values during rest and controlled breathing showed a high correlation (r = 0.93, standard error of the estimation = 2.5 ms/mmHg) with the phenylephrine test slope. In severe CHF patients the beta index proposed, evaluated during rest and controlled breathing, may improve the baroreflex gain estimation and provide a non invasive assessment method that might be useful in gauging prognosis.
| Original language | English |
|---|---|
| Title of host publication | Computers in Cardiology |
| Publisher | IEEE Comp Soc |
| Pages | 203-206 |
| Number of pages | 4 |
| Publication status | Published - 1997 |
| Event | Proceedings of the 1997 24th Annual Meeting on Computers in Cardiology - Lund, Sweden Duration: Sep 7 1997 → Sep 10 1997 |
Other
| Other | Proceedings of the 1997 24th Annual Meeting on Computers in Cardiology |
|---|---|
| City | Lund, Sweden |
| Period | 9/7/97 → 9/10/97 |
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ASJC Scopus subject areas
- Software
- Cardiology and Cardiovascular Medicine
Cite this
Baroreflex sensitivity in cardiac patients with Chronic Congestive Heart Failure : Towards a non invasive assessment method. / Colombo, R.; Mazzuero, G.; Lanfranchi, P.; Spinatonda, G.; Giannuzzi, P.; Minuco, G.
Computers in Cardiology. IEEE Comp Soc, 1997. p. 203-206.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Baroreflex sensitivity in cardiac patients with Chronic Congestive Heart Failure
T2 - Towards a non invasive assessment method
AU - Colombo, R.
AU - Mazzuero, G.
AU - Lanfranchi, P.
AU - Spinatonda, G.
AU - Giannuzzi, P.
AU - Minuco, G.
PY - 1997
Y1 - 1997
N2 - Spectral analysis of RR interval and systolic arterial pressure variability was applied for the non invasive assessment of the baroreflex gain in Congestive Chronic Heart Failure (CHF). Forty-nine CHF patients were studied during rest, controlled breathing and head-up tilt. The alpha index, a non invasive measure of the overall gain of the RR to systolic arterial pressure (SAP) relationship, and a modified version called beta, incorporating the weighted coherence function, were computed in the low (LF) and high (HF) frequency bands by spectral analysis, and compared with the phenylephrine test slope. A linear model fitted on the beta index values during rest and controlled breathing showed a high correlation (r = 0.93, standard error of the estimation = 2.5 ms/mmHg) with the phenylephrine test slope. In severe CHF patients the beta index proposed, evaluated during rest and controlled breathing, may improve the baroreflex gain estimation and provide a non invasive assessment method that might be useful in gauging prognosis.
AB - Spectral analysis of RR interval and systolic arterial pressure variability was applied for the non invasive assessment of the baroreflex gain in Congestive Chronic Heart Failure (CHF). Forty-nine CHF patients were studied during rest, controlled breathing and head-up tilt. The alpha index, a non invasive measure of the overall gain of the RR to systolic arterial pressure (SAP) relationship, and a modified version called beta, incorporating the weighted coherence function, were computed in the low (LF) and high (HF) frequency bands by spectral analysis, and compared with the phenylephrine test slope. A linear model fitted on the beta index values during rest and controlled breathing showed a high correlation (r = 0.93, standard error of the estimation = 2.5 ms/mmHg) with the phenylephrine test slope. In severe CHF patients the beta index proposed, evaluated during rest and controlled breathing, may improve the baroreflex gain estimation and provide a non invasive assessment method that might be useful in gauging prognosis.
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M3 - Conference contribution
SP - 203
EP - 206
BT - Computers in Cardiology
PB - IEEE Comp Soc
ER -