Basal-cell skin carcinoma following brachytherapy (226Ra) and orthovoltage X-ray therapy for flat angioma

M. Caccialanza, R. Piccinno, G. Pistritto, L. Gnecchi

Research output: Contribution to journalArticlepeer-review

Abstract

The authors report the case of a 62-year-old woman exhibiting, since birth, a flat skin angioma on the left leg. Between 17 and 20 years of age, the patient was submitted to three successive radiotherapy courses, by orthovoltage X-rays, 226Ra as needles inserted into suitable applicators and contact X-ray therapy. The total dose administered was regarded as having been approximately 16 Gy. At the irradiated area, chronic radiodermatitis occurred and, about 33 years after the end of treatment, the skin ulcerated in correspondence with the site of application of the radioactive preparations. Histopathological examination was positive for basal-cell carcinoma. Other traumatic or carcinogenic factors could be ruled out. The role of the past radiotherapy in the occurrence of the skin tumours is discussed, also in the light of literature findings.

Original languageEnglish
Pages (from-to)103-106
Number of pages4
JournalSkin Cancer
Volume7
Issue number2
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Dermatology
  • Oncology

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