Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication

R. M. Lacatena, G. Cesareni

Research output: Contribution to journalArticle

121 Citations (Scopus)

Abstract

Four single base pair mutations in the region that codes for RNA I create new incompatibility groups while preserving the mechanism of control of initiation of DNA replication in a ColE1-type plasmid. Sequence analysis of these base substitutions points to the primary importance of the central loop of the cloverleaf structure of RNA I in this control mechanism.

Original languageEnglish
Pages (from-to)623-626
Number of pages4
JournalNature
Volume294
Issue number5842
DOIs
Publication statusPublished - 1981

Fingerprint

Base Pairing
DNA Replication
Sequence Analysis
Plasmids
Mutation
RNA I

ASJC Scopus subject areas

  • General

Cite this

Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication. / Lacatena, R. M.; Cesareni, G.

In: Nature, Vol. 294, No. 5842, 1981, p. 623-626.

Research output: Contribution to journalArticle

@article{0b0a469c63574a77be8a043e81238e9a,
title = "Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication",
abstract = "Four single base pair mutations in the region that codes for RNA I create new incompatibility groups while preserving the mechanism of control of initiation of DNA replication in a ColE1-type plasmid. Sequence analysis of these base substitutions points to the primary importance of the central loop of the cloverleaf structure of RNA I in this control mechanism.",
author = "Lacatena, {R. M.} and G. Cesareni",
year = "1981",
doi = "10.1038/294623a0",
language = "English",
volume = "294",
pages = "623--626",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "5842",

}

TY - JOUR

T1 - Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication

AU - Lacatena, R. M.

AU - Cesareni, G.

PY - 1981

Y1 - 1981

N2 - Four single base pair mutations in the region that codes for RNA I create new incompatibility groups while preserving the mechanism of control of initiation of DNA replication in a ColE1-type plasmid. Sequence analysis of these base substitutions points to the primary importance of the central loop of the cloverleaf structure of RNA I in this control mechanism.

AB - Four single base pair mutations in the region that codes for RNA I create new incompatibility groups while preserving the mechanism of control of initiation of DNA replication in a ColE1-type plasmid. Sequence analysis of these base substitutions points to the primary importance of the central loop of the cloverleaf structure of RNA I in this control mechanism.

UR - http://www.scopus.com/inward/record.url?scp=0019883537&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019883537&partnerID=8YFLogxK

U2 - 10.1038/294623a0

DO - 10.1038/294623a0

M3 - Article

C2 - 6171736

AN - SCOPUS:0019883537

VL - 294

SP - 623

EP - 626

JO - Nature

JF - Nature

SN - 0028-0836

IS - 5842

ER -