Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication

R. M. Lacatena, G. Cesareni

Research output: Contribution to journalArticlepeer-review

Abstract

Four single base pair mutations in the region that codes for RNA I create new incompatibility groups while preserving the mechanism of control of initiation of DNA replication in a ColE1-type plasmid. Sequence analysis of these base substitutions points to the primary importance of the central loop of the cloverleaf structure of RNA I in this control mechanism.

Original languageEnglish
Pages (from-to)623-626
Number of pages4
JournalNature
Volume294
Issue number5842
DOIs
Publication statusPublished - 1981

ASJC Scopus subject areas

  • General

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