Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication

R. M. Lacatena, G. Cesareni

Research output: Contribution to journal › Article

121 Citations (Scopus)

Abstract

Four single base pair mutations in the region that codes for RNA I create new incompatibility groups while preserving the mechanism of control of initiation of DNA replication in a ColE1-type plasmid. Sequence analysis of these base substitutions points to the primary importance of the central loop of the cloverleaf structure of RNA I in this control mechanism.

Original languageEnglish
Pages (from-to)623-626
Number of pages4
JournalNature
Volume294
Issue number5842
DOIs
Publication statusPublished - 1981

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Base Pairing
DNA Replication
Sequence Analysis
Plasmids
Mutation
RNA I

ASJC Scopus subject areas

  • General

Cite this

Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication. / Lacatena, R. M.; Cesareni, G.

In: Nature, Vol. 294, No. 5842, 1981, p. 623-626.

Research output: Contribution to journal › Article

Lacatena, RM & Cesareni, G 1981, 'Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication', Nature, vol. 294, no. 5842, pp. 623-626. https://doi.org/10.1038/294623a0
Lacatena RM, Cesareni G. Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication. Nature. 1981;294(5842):623-626. https://doi.org/10.1038/294623a0
Lacatena, R. M. ; Cesareni, G. / Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication. In: Nature. 1981 ; Vol. 294, No. 5842. pp. 623-626.
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