Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication

R. M. Lacatena; G. Cesareni

doi:10.1038/294623a0

Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication

R. M. Lacatena, G. Cesareni

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

Four single base pair mutations in the region that codes for RNA I create new incompatibility groups while preserving the mechanism of control of initiation of DNA replication in a ColE1-type plasmid. Sequence analysis of these base substitutions points to the primary importance of the central loop of the cloverleaf structure of RNA I in this control mechanism.

Original language	English
Pages (from-to)	623-626
Number of pages	4
Journal	Nature
Volume	294
Issue number	5842
DOIs	https://doi.org/10.1038/294623a0
Publication status	Published - 1981

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title = "Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication",

abstract = "Four single base pair mutations in the region that codes for RNA I create new incompatibility groups while preserving the mechanism of control of initiation of DNA replication in a ColE1-type plasmid. Sequence analysis of these base substitutions points to the primary importance of the central loop of the cloverleaf structure of RNA I in this control mechanism.",

author = "Lacatena, {R. M.} and G. Cesareni",

year = "1981",

doi = "10.1038/294623a0",

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volume = "294",

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journal = "Nature",

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AU - Lacatena, R. M.

AU - Cesareni, G.

PY - 1981

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AB - Four single base pair mutations in the region that codes for RNA I create new incompatibility groups while preserving the mechanism of control of initiation of DNA replication in a ColE1-type plasmid. Sequence analysis of these base substitutions points to the primary importance of the central loop of the cloverleaf structure of RNA I in this control mechanism.

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JO - Nature

JF - Nature

SN - 0028-0836

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Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication

Abstract

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