Abstract
Four single base pair mutations in the region that codes for RNA I create new incompatibility groups while preserving the mechanism of control of initiation of DNA replication in a ColE1-type plasmid. Sequence analysis of these base substitutions points to the primary importance of the central loop of the cloverleaf structure of RNA I in this control mechanism.
Original language | English |
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Pages (from-to) | 623-626 |
Number of pages | 4 |
Journal | Nature |
Volume | 294 |
Issue number | 5842 |
DOIs | |
Publication status | Published - 1981 |
ASJC Scopus subject areas
- General