Basic concepts of advanced MRI techniques

Elisabetta Pagani, Alberto Bizzi, Francesco Salle, Nicola Stefano, Massimo Filippi

Research output: Contribution to journalArticlepeer-review


An overview is given of magnetic resonance (MR) techniques sensitized to diffusion, flow, magnetization transfer effect, and local field inhomogeneities induced by physiological changes, that can be viewed, in the clinical practice, as advanced because of their challenging implementation and interpretation. These techniques are known as diffusion-weighted, perfusion, magnetization transfer, functional MRI and MR spectroscopy. An important issue is that they can provide quantitative estimates of structural and functional characteristics that are below the voxel resolution. This review does not deal with the basic concepts of the MR physics and the description of the available acquisition and postprocessing methods, but hopefully provides an adequate background to readers and hence facilitate the understanding of the following clinical contributions.

Original languageEnglish
JournalNeurological Sciences
Issue numberSUPPL. 3
Publication statusPublished - Oct 2008


  • Diffusion
  • Functional MRI
  • Magnetic resonance imaging
  • Magnetization transfer
  • Perfusion
  • Proton MR spectroscopy

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology


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