Basics of Confocal Microscopy and the Complexity of Diagnosing Skin Tumors: New Imaging Tools in Clinical Practice, Diagnostic Workflows, Cost-Estimate, and New Trends

Syril Keena T Que, Jane M. Grant-Kels, Caterina Longo, Giovanni Pellacani

Research output: Contribution to journalReview article


The use of reflectance confocal microscopy (RCM) and other noninvasive imaging devices can potentially streamline clinical care, leading to more precise and efficient management of skin cancer. This article explores the potential role of RCM in cutaneous oncology, as an adjunct to more established techniques of detecting and monitoring for skin cancer, such as dermoscopy and total body photography. Discussed are current barriers to the adoption of RCM, diagnostic workflows and standards of care in the United States and Europe, and medicolegal issues. The potential role of RCM and other similar technological innovations in the enhancement of dermatologic care is evaluated.

Original languageEnglish
Pages (from-to)367-375
Number of pages9
JournalDermatologic Clinics
Issue number4
Publication statusPublished - Oct 1 2016



  • Confocal microscopy
  • Cost-estimates
  • Medicolegal issues
  • Melanoma
  • Nonmelanoma skin cancer
  • Standard of care

ASJC Scopus subject areas

  • Dermatology

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