TY - JOUR
T1 - Bedaquiline and Delamanid Combination Treatment of 5 Patients with Pulmonary Extensively Drug-Resistant Tuberculosis
AU - Maryandyshev, Andrey
AU - Pontali, Emanuele
AU - Tiberi, Simon
AU - Akkerman, Onno
AU - Ganatra, Shashank
AU - Sadutshang, Tsetan Dorji
AU - Alffenaar, Jan-Willem
AU - Amale, Rohit
AU - Mullerpattan, Jai
AU - Topgyal, Sonam
AU - Udwadia, Zarir Farokh
AU - Centis, Rosella
AU - D'Ambrosio, Lia
AU - Sotgiu, Giovanni
AU - Migliori, Giovanni Battista
PY - 2017/10
Y1 - 2017/10
N2 - We report the experiences of 5 patients taking bedaquiline with delamanid in combination: 1 patient was cured; 3 culture converted, with 2 continuing and 1 changing therapy; and 1 died from respiratory insufficiency. For 2 patients, QT-interval prolongation but no arrhythmias occurred. Use of this therapy is justified for patients with limited options.
AB - We report the experiences of 5 patients taking bedaquiline with delamanid in combination: 1 patient was cured; 3 culture converted, with 2 continuing and 1 changing therapy; and 1 died from respiratory insufficiency. For 2 patients, QT-interval prolongation but no arrhythmias occurred. Use of this therapy is justified for patients with limited options.
KW - Journal Article
U2 - 10.3201/eid2310.170834
DO - 10.3201/eid2310.170834
M3 - Article
C2 - 28758888
VL - 23
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
SN - 1080-6040
IS - 10
ER -