Behavior of gangliosides on dialysis

R. Ghidoni, S. Sonnino, G. Tettamanti

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Mixed brain gangliosides or individual ganglioside GM1 were dissolved in one of the following solvents: (a) water, (b) 0.1 M aqueous KC1, or (c) methanol-aqueous 0.1 M KC1 at concentrations ranging from 10-8 to 10-3 M, and were submitted to dialysis against distilled water for up to 4 days. No significant loss of gangliosides on dialysis was observed when gangliosides were dissolved in water or 0.1 M aqueous KC1, but a loss occurred when the ganglioside solution contained methanol; the loss was greater at the lowest ganglioside concentration. However, losses ceased to occur after 1 day when methanol was removed from the dialysis sac.

Original languageEnglish
Pages (from-to)820-822
Number of pages3
JournalLipids
Volume13
Issue number11
DOIs
Publication statusPublished - Nov 1978

Fingerprint

gangliosides
Dialysis
Gangliosides
dialysis
Methanol
methanol
water
Water
G(M1) Ganglioside
Brain
brain

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Food Science

Cite this

Ghidoni, R., Sonnino, S., & Tettamanti, G. (1978). Behavior of gangliosides on dialysis. Lipids, 13(11), 820-822. https://doi.org/10.1007/BF02533483

Behavior of gangliosides on dialysis. / Ghidoni, R.; Sonnino, S.; Tettamanti, G.

In: Lipids, Vol. 13, No. 11, 11.1978, p. 820-822.

Research output: Contribution to journalArticle

Ghidoni, R, Sonnino, S & Tettamanti, G 1978, 'Behavior of gangliosides on dialysis', Lipids, vol. 13, no. 11, pp. 820-822. https://doi.org/10.1007/BF02533483
Ghidoni R, Sonnino S, Tettamanti G. Behavior of gangliosides on dialysis. Lipids. 1978 Nov;13(11):820-822. https://doi.org/10.1007/BF02533483
Ghidoni, R. ; Sonnino, S. ; Tettamanti, G. / Behavior of gangliosides on dialysis. In: Lipids. 1978 ; Vol. 13, No. 11. pp. 820-822.
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