Abstract
Mixed brain gangliosides or individual ganglioside GM1 were dissolved in one of the following solvents: (a) water, (b) 0.1 M aqueous KC1, or (c) methanol-aqueous 0.1 M KC1 at concentrations ranging from 10-8 to 10-3 M, and were submitted to dialysis against distilled water for up to 4 days. No significant loss of gangliosides on dialysis was observed when gangliosides were dissolved in water or 0.1 M aqueous KC1, but a loss occurred when the ganglioside solution contained methanol; the loss was greater at the lowest ganglioside concentration. However, losses ceased to occur after 1 day when methanol was removed from the dialysis sac.
| Original language | English |
|---|---|
| Pages (from-to) | 820-822 |
| Number of pages | 3 |
| Journal | Lipids |
| Volume | 13 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - Nov 1978 |
Fingerprint
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Biochemistry
- Biochemistry, Genetics and Molecular Biology(all)
- Food Science
Cite this
Behavior of gangliosides on dialysis. / Ghidoni, R.; Sonnino, S.; Tettamanti, G.
In: Lipids, Vol. 13, No. 11, 11.1978, p. 820-822.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Behavior of gangliosides on dialysis
AU - Ghidoni, R.
AU - Sonnino, S.
AU - Tettamanti, G.
PY - 1978/11
Y1 - 1978/11
N2 - Mixed brain gangliosides or individual ganglioside GM1 were dissolved in one of the following solvents: (a) water, (b) 0.1 M aqueous KC1, or (c) methanol-aqueous 0.1 M KC1 at concentrations ranging from 10-8 to 10-3 M, and were submitted to dialysis against distilled water for up to 4 days. No significant loss of gangliosides on dialysis was observed when gangliosides were dissolved in water or 0.1 M aqueous KC1, but a loss occurred when the ganglioside solution contained methanol; the loss was greater at the lowest ganglioside concentration. However, losses ceased to occur after 1 day when methanol was removed from the dialysis sac.
AB - Mixed brain gangliosides or individual ganglioside GM1 were dissolved in one of the following solvents: (a) water, (b) 0.1 M aqueous KC1, or (c) methanol-aqueous 0.1 M KC1 at concentrations ranging from 10-8 to 10-3 M, and were submitted to dialysis against distilled water for up to 4 days. No significant loss of gangliosides on dialysis was observed when gangliosides were dissolved in water or 0.1 M aqueous KC1, but a loss occurred when the ganglioside solution contained methanol; the loss was greater at the lowest ganglioside concentration. However, losses ceased to occur after 1 day when methanol was removed from the dialysis sac.
UR - http://www.scopus.com/inward/record.url?scp=0018253203&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018253203&partnerID=8YFLogxK
U2 - 10.1007/BF02533483
DO - 10.1007/BF02533483
M3 - Article
AN - SCOPUS:0018253203
VL - 13
SP - 820
EP - 822
JO - Lipids
JF - Lipids
SN - 0024-4201
IS - 11
ER -