Behavior of living human neural networks on microelectrode array support

R. Pizzi, F. Gelain, A. Fantasia, D. Rossetti, A. Vescovi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Researchers of the Department of Information Technologies of the University of Milano and of the Stem Cells Research Institute of the DIBIT-S. Raffaele Milano are experimenting the growth of human neural networks of stem cells on a MEA (Microelectrode Array) support. The Microelectrode arrays (MEAs) are constituted by a glass support where a set of tungsten electrodes is inserted. We connected the microelectrodes following the architecture of classical artificial neural networks, in particular Kohonen and Hopfield networks. The neurons are stimulated following digital patterns and the output signals are analysed to evaluate the possibility of organized reactions by the natural neurons. The neurons reply selectively to different patterns and show similar reactions in front of the presentation of identical or similar patterns. These results allow to design further experiments that improve the neural networks capabilities and to test the possibility of utilizing the organized answers of the neurons in several ways.

Original languageEnglish
Title of host publication2004 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2004
EditorsM. Laudon, B. Romanowicz
Pages232-235
Number of pages4
Volume1
Publication statusPublished - 2004
Event2004 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2004 - Boston, MA, United States
Duration: Mar 7 2004Mar 11 2004

Other

Other2004 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2004
CountryUnited States
CityBoston, MA
Period3/7/043/11/04

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Keywords

  • Learning
  • Microelectrode arrays
  • Neural networks
  • Stem cells

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Pizzi, R., Gelain, F., Fantasia, A., Rossetti, D., & Vescovi, A. (2004). Behavior of living human neural networks on microelectrode array support. In M. Laudon, & B. Romanowicz (Eds.), 2004 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2004 (Vol. 1, pp. 232-235)