Behavior of prealbumin in the acute phase of polymyalgia rheumatica treated with 6-methylprednisolone

Luca Puccetti; Amalia Lucchetti; Paola Barbieri; Daniela Melchiorre; Mauro Zuccotti; Gabriella Petrini; Giorgio Marotta; Elisabetta Remorini; Maria Laura Ciompi

doi:10.1007/BF02871814

Behavior of prealbumin in the acute phase of polymyalgia rheumatica treated with 6-methylprednisolone

Luca Puccetti, Amalia Lucchetti, Paola Barbieri, Daniela Melchiorre, Mauro Zuccotti, Gabriella Petrini, Giorgio Marotta, Elisabetta Remorini, Maria Laura Ciompi

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

Serum levels of prealbumin, fibronectin, fibrinogen, α₁-acid glycoprotein, C-reactive protein, immunoglobulins, and white blood cell count were prospectively studied in 33 patients affected by polymyalgia rheumatica during the first 45 days of treatment with 6-methylprednisolone. Almost all parameters considered, except for fibronectin and IgM, settled within the normal range fairly quickly, while prealbumin showed a specular course compared with the other reactants. This behavior reflected the improvement of clinical symptoms registered in all patients after steroid treatment. Finally, the genesis of the low baseline prealbumin levels found in polymyalgia rheumatica/giant cell arteritis and their behavior during treatment are discussed.

Original language	English
Pages (from-to)	251-258
Number of pages	8
Journal	La Ricerca in Clinica e in Laboratorio
Volume	19
Issue number	1
DOIs	https://doi.org/10.1007/BF02871814
Publication status	Published - Dec 1989

Keywords

Acute phase proteins
Polymyalgia rheumatica
Prealbumin
Protein energy malnutrition
Steroid treatment

ASJC Scopus subject areas

Clinical Biochemistry

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10.1007/BF02871814

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Behavior of prealbumin in the acute phase of polymyalgia rheumatica treated with 6-methylprednisolone. / Puccetti, Luca; Lucchetti, Amalia; Barbieri, Paola; Melchiorre, Daniela; Zuccotti, Mauro; Petrini, Gabriella; Marotta, Giorgio; Remorini, Elisabetta; Ciompi, Maria Laura.

In: La Ricerca in Clinica e in Laboratorio, Vol. 19, No. 1, 12.1989, p. 251-258.

Research output: Contribution to journal › Article › peer-review

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abstract = "Serum levels of prealbumin, fibronectin, fibrinogen, α1-acid glycoprotein, C-reactive protein, immunoglobulins, and white blood cell count were prospectively studied in 33 patients affected by polymyalgia rheumatica during the first 45 days of treatment with 6-methylprednisolone. Almost all parameters considered, except for fibronectin and IgM, settled within the normal range fairly quickly, while prealbumin showed a specular course compared with the other reactants. This behavior reflected the improvement of clinical symptoms registered in all patients after steroid treatment. Finally, the genesis of the low baseline prealbumin levels found in polymyalgia rheumatica/giant cell arteritis and their behavior during treatment are discussed.",

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AU - Zuccotti, Mauro

AU - Petrini, Gabriella

AU - Marotta, Giorgio

AU - Remorini, Elisabetta

AU - Ciompi, Maria Laura

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AB - Serum levels of prealbumin, fibronectin, fibrinogen, α1-acid glycoprotein, C-reactive protein, immunoglobulins, and white blood cell count were prospectively studied in 33 patients affected by polymyalgia rheumatica during the first 45 days of treatment with 6-methylprednisolone. Almost all parameters considered, except for fibronectin and IgM, settled within the normal range fairly quickly, while prealbumin showed a specular course compared with the other reactants. This behavior reflected the improvement of clinical symptoms registered in all patients after steroid treatment. Finally, the genesis of the low baseline prealbumin levels found in polymyalgia rheumatica/giant cell arteritis and their behavior during treatment are discussed.

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Behavior of prealbumin in the acute phase of polymyalgia rheumatica treated with 6-methylprednisolone

Abstract

Keywords

ASJC Scopus subject areas

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