Behaviour disorder caused by Cushing's syndrome in an older person

S. Damanti, C. Abbate, I. Chiodini, M. Cesari, T. Nestola, G. Belloni, C. Mandelli, D. Mari, T. Lucchi

Research output: Contribution to journalArticle

Abstract

An 81-year-old woman was hospitalised for behavioural disorders that had been progressively emerging over a period of few weeks. The symptoms appeared to worsen over time. A diagnosis of vascular dementia, complicated by psychosis, was initially hypothesised. The inefficacy of the antipsychotic/benzodiazepine medications used, along with the presence of hypertension, hypokalaemia and metabolic alkalosis (resistant to pharmacological attempts of correction), as well as the hirsutism and the development of several infections, led us to consider Cushing's syndrome. Endocrinological analysis suggested ectopic adrenocorticotropic hormone (ACTH) secretion. Although endogenous Cushing's syndrome is rare in older people, it should always be considered among the differential diagnosis of behavioural disorders.

Original languageEnglish
Pages (from-to)905-906
Number of pages2
JournalAge and Ageing
Volume47
Issue number6
DOIs
Publication statusPublished - Nov 1 2018

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Cushing Syndrome
Mental Disorders
Ectopic Hormones
Alkalosis
Hirsutism
Vascular Dementia
Hypokalemia
Benzodiazepines
Psychotic Disorders
Adrenocorticotropic Hormone
Antipsychotic Agents
Differential Diagnosis
Pharmacology
Hypertension
Infection

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

Cite this

Behaviour disorder caused by Cushing's syndrome in an older person. / Damanti, S.; Abbate, C.; Chiodini, I.; Cesari, M.; Nestola, T.; Belloni, G.; Mandelli, C.; Mari, D.; Lucchi, T.

In: Age and Ageing, Vol. 47, No. 6, 01.11.2018, p. 905-906.

Research output: Contribution to journalArticle

Damanti, S. ; Abbate, C. ; Chiodini, I. ; Cesari, M. ; Nestola, T. ; Belloni, G. ; Mandelli, C. ; Mari, D. ; Lucchi, T. / Behaviour disorder caused by Cushing's syndrome in an older person. In: Age and Ageing. 2018 ; Vol. 47, No. 6. pp. 905-906.
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