The Framingham study and the Israeli Ischemic Heart Disease study reported that HDL-cholesterol is negatively related to the ischemic heart disease incidence in elderly subjects. We studied total HDL, HDL2 and HDL3-cholesterol, lipoprotein lipase, both hepatic and extrahepatic, in 80 subjects, of both sexes, aged more than 65 years. Men older than 75 years old have high levels of HDL2 cholesterol, and decreased hepatic lipase activity was observed. In women of the same age high levels of HDL3-cholesterol and increased hepatic lipase activity were observed. In elderly men there is a negative correlation between hepatic lipase activity and HDL2-cholesterol levels. Our results can be explained on the basis of the HDL metabolic cycle proposed by Nikkila.
|Translated title of the contribution||Behaviour of HDL2, HDL3, cholesterol and hepatic and extrahepatic lipoprotein lipase activities in the elderly|
|Number of pages||6|
|Journal||Giornale di Gerontologia|
|Publication status||Published - 1985|
ASJC Scopus subject areas
- Geriatrics and Gerontology