TY - JOUR
T1 - Behavioural and EEG effects induced by an amphetamine like substance (cathinone) in rats
AU - Berardelli, A.
AU - Capocaccia, L.
AU - Pacitti, C.
AU - Tancredi, V.
AU - Quinteri, F.
AU - Elmi, Abdullahi S.
PY - 1980
Y1 - 1980
N2 - The effects of Cathinone, administered peritoneally, on the motor and electroencephalographic activity of the rat have been studied. This substance, recently isolated from the leaves of the Catha Edulis, presents chemical characteristics common to amphetamine. Cathinone has demonstrated a pharmacologic action somewhat less than that of amphetamine. It provokes the appearance of tremor and a stereotyped motor behaviour at low doses and seizures at high doses. The cerebral electrical activity is modified in the sense of activation patterns accompanied, at higher doses, by single pseudoperiodic sharp waves.
AB - The effects of Cathinone, administered peritoneally, on the motor and electroencephalographic activity of the rat have been studied. This substance, recently isolated from the leaves of the Catha Edulis, presents chemical characteristics common to amphetamine. Cathinone has demonstrated a pharmacologic action somewhat less than that of amphetamine. It provokes the appearance of tremor and a stereotyped motor behaviour at low doses and seizures at high doses. The cerebral electrical activity is modified in the sense of activation patterns accompanied, at higher doses, by single pseudoperiodic sharp waves.
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U2 - 10.1016/S0031-6989(80)80163-9
DO - 10.1016/S0031-6989(80)80163-9
M3 - Article
C2 - 7192407
AN - SCOPUS:0019157402
VL - 12
SP - 959
EP - 964
JO - Pharmacological Research
JF - Pharmacological Research
SN - 1043-6618
IS - 10
ER -