Behavioural and EEG effects induced by an amphetamine like substance (cathinone) in rats

A. Berardelli; L. Capocaccia; C. Pacitti; V. Tancredi; F. Quinteri; Abdullahi S. Elmi

doi:10.1016/S0031-6989(80)80163-9

Behavioural and EEG effects induced by an amphetamine like substance (cathinone) in rats

A. Berardelli, L. Capocaccia, C. Pacitti, V. Tancredi, F. Quinteri, Abdullahi S. Elmi

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Abstract

The effects of Cathinone, administered peritoneally, on the motor and electroencephalographic activity of the rat have been studied. This substance, recently isolated from the leaves of the Catha Edulis, presents chemical characteristics common to amphetamine. Cathinone has demonstrated a pharmacologic action somewhat less than that of amphetamine. It provokes the appearance of tremor and a stereotyped motor behaviour at low doses and seizures at high doses. The cerebral electrical activity is modified in the sense of activation patterns accompanied, at higher doses, by single pseudoperiodic sharp waves.

Original language	English
Pages (from-to)	959-964
Number of pages	6
Journal	Pharmacological Research Communications
Volume	12
Issue number	10
DOIs	https://doi.org/10.1016/S0031-6989(80)80163-9
Publication status	Published - 1980

ASJC Scopus subject areas

Pharmacology

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title = "Behavioural and EEG effects induced by an amphetamine like substance (cathinone) in rats",

abstract = "The effects of Cathinone, administered peritoneally, on the motor and electroencephalographic activity of the rat have been studied. This substance, recently isolated from the leaves of the Catha Edulis, presents chemical characteristics common to amphetamine. Cathinone has demonstrated a pharmacologic action somewhat less than that of amphetamine. It provokes the appearance of tremor and a stereotyped motor behaviour at low doses and seizures at high doses. The cerebral electrical activity is modified in the sense of activation patterns accompanied, at higher doses, by single pseudoperiodic sharp waves.",

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T1 - Behavioural and EEG effects induced by an amphetamine like substance (cathinone) in rats

AU - Berardelli, A.

AU - Capocaccia, L.

AU - Pacitti, C.

AU - Tancredi, V.

AU - Quinteri, F.

AU - Elmi, Abdullahi S.

PY - 1980

Y1 - 1980

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AB - The effects of Cathinone, administered peritoneally, on the motor and electroencephalographic activity of the rat have been studied. This substance, recently isolated from the leaves of the Catha Edulis, presents chemical characteristics common to amphetamine. Cathinone has demonstrated a pharmacologic action somewhat less than that of amphetamine. It provokes the appearance of tremor and a stereotyped motor behaviour at low doses and seizures at high doses. The cerebral electrical activity is modified in the sense of activation patterns accompanied, at higher doses, by single pseudoperiodic sharp waves.

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