Benefit of aspirin plus moderate-intensity oral anti-coagulation compared with aspirin alone after acute coronary syndromes

Felicita Andreotti, Luca Testa

Research output: Contribution to journalArticlepeer-review

Abstract

The role combination therapy with an oral anticoagulant and aspirin for patients recovering from an acute coronary syndrome is still being debated. The results of our meta-analysis showed that treatment with aspirin plus warfarin at international normalized ratio values between 2 and 3 significantly reduces the risk of major adverse events compared with aspirin alone but also increases the risk of major bleeding. For every 100 patients receiving combination therapy, approximately 3 major adverse events are prevented and 1 major hemorrhage occurs.

Original languageEnglish
Pages (from-to)22-26
Number of pages5
JournalCardiology Review
Volume23
Issue number11
Publication statusPublished - Nov 2006

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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