Benefits and shortcomings of superselective transarterial embolization of renal tumors before zero ischemia laparoscopic partial nephrectomy

L. D'Urso, G. Simone, R. Rosso, D. Collura, E. Castelli, A. Giacobbe, G. L. Muto, S. Comelli, D. Savio, G. Muto

Research output: Contribution to journalArticlepeer-review

Abstract

Aims To report feasibility, safety and effectiveness of "zero-ischemia" laparoscopic partial nephrectomy (LPN) following preoperative superselective transarterial embolization (STE) for clinical T1 renal tumors. Methods We retrospectively reviewed perioperative data of 23 consecutive patients, who underwent STE prior LPN between March 2010 and November 2012 for incidental clinical T1 renal mass. STE was performed by two experienced radiologists the day before surgery. Surgical procedures were performed in extended flank position, transperitoneally, by a single surgeon. Results Mean patients age was 68 years (range 56-74), mean tumor size was 3.5 cm (range 2.2-6.3 cm). STE was successfully completed in 16 patients 12-15 h before surgery. In 4 cases STE failed to provide a complete occlusion of all feeding arteries, while in 3 cases the ischemic area was larger than expected. LPN was successfully completed in all patients but one where open conversion was necessary; a "zero-ischemia" approach was performed in 19/23 patients (82.6%) while hilar clamp was necessary in 4 cases, with a mean warm-ischemia time of 14.8 min (range 5-22). Mean operative time was 123 min (range 115-130) and mean intraoperative blood loss was 250 mL (range 20-450). No patient experienced postoperative acute renal failure and no patient developed new onset IV stage chronic kidney disease at 1-yr follow-up. Conclusions STE is a viable option to perform "zero-ischemia" LPN at beginning of learning curve; however, hilar clamp was necessary to achieve a relatively blood-less field in 17.4% of cases.

Original languageEnglish
Pages (from-to)1731-1737
Number of pages7
JournalEuropean Journal of Surgical Oncology
Volume40
Issue number12
DOIs
Publication statusPublished - Dec 1 2014

Keywords

  • Embolization
  • Kidney neoplasm
  • Laparoscopic partial nephrectomy
  • Off-clamp
  • Zero ischemia

ASJC Scopus subject areas

  • Oncology
  • Surgery
  • Medicine(all)

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