Benefits of breastfeeding in cystic fibrosis: A single-centre follow-up survey

Carla Colombo, Diana Costantini, Laura Zazzeron, Nadia Faelli, Maria Chiara Russo, Diana Ghisleni, Italo Gatelli, Marcello Giovannini, Enrica Riva, Rolf Zetterström, Carlo Agostoni

Research output: Contribution to journalArticle


Aim: To study the effect of breastfeeding (BF) on growth, lung function and number of infections during the first 3 years of life in children with cystic fibrosis (CF). Material and methods: One hundred forty-six CF patients, 5-18 years old, were recruited at their annual care visit. Information about infant feeding, psychosocial and socioeconomic conditions and smoking exposure was obtained by interviews. Anthropometric parameters at 1 year of age and the number of infections and hospitalisations during the first 3 years of life were obtained from clinical charts. Anthropometrics and pulmonary function parameters were obtained at enrolment. Results: In CF patients, particularly those with pancreatic insufficiency, the prevalence of BF was lower than the general Italian population. After multivariate analysis patients with prolonged BF showed higher values of CED expiratory volume in 1 sec (FEV-1) (p = 0.001) and a lower number of infections during the first 3 years of life (p = 0.098). Conclusion: Prolonged BF is beneficial in children with CF and may protect them against decline of pulmonary function. Particular attention should be paid to promote BF in infants with CF.

Original languageEnglish
Pages (from-to)1228-1232
Number of pages5
JournalActa Paediatrica, International Journal of Paediatrics
Issue number8
Publication statusPublished - Aug 2007



  • Cystic fibrosis
  • Human milk
  • Infections
  • Lung function
  • Pancreatic function

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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