We present three families where 7 subjects, three couples of sibling and one cousin, were all affected from complex partial seizures but three of them also from secondary generalized tonic-clonic attacks. Generalized primary epilepsy (GM and Juvenile Myoclonic) and febrile convulsions were disclosed in some members of their families. From the neurological point of view all the patients are normal and no mental retardation is overt but a modest one in two of them. Brain CT was negative in all of them. The interictal EEGs show a normal background activity with focalized paroxysms over the frontal and/or temporal regions, but in four of the subjects there are some genetic features as generalized spike-and-wave discharges during wakefulness and sleep or rather occipital spike-and-wave discharges after eyes' closing, either peculiar respectively of generalized primary as well as of idiopathic partial epilepsies. Therefore we believe about the existence of a benign epileptic syndrome characterized by familiar complex partial seizures, a syndrome that may be considered to have prognosis anyway intermediary between the idiopathic partial syndromes and the symptomatic epilepsies.
|Translated title of the contribution||Benign epileptic syndrome with familial complex partial seizures: A clinical and EEG study of three families|
|Title of host publication||Bollettino - Lega Italiana contro l'Epilessia|
|Number of pages||6|
|Publication status||Published - 1989|
ASJC Scopus subject areas
- Clinical Neurology