Benign multicystic mesothelial proliferation of the peritoneum

Immunohistochemical and electron microscopical study of a case and review of the literature

G. Pelosi, M. Zannoni, F. Caprioli, L. Faccincani, M. G. Battistoni, G. Balercia, L. Bontempini

Research output: Contribution to journalArticle

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Abstract

We report a case of benign multicystic mesothelial proliferation (the so-called multicystic peritoneal mesothelioma) arising multifocally in the abdomen of a 46-year-old white man. His anamnesis showed an 8-year history of intermittent pain in the right lower abdominal quadrant. Mucin stains, immunohistochemistry, and electron microscopy confirmed the mesothelial origin of the lesion. Review of the available literature allowed us to find another 85 reported cases of benign multicystic mesothelial proliferations of the peritoneum. Out of these cases, eighteen only occurred in men, the majority being reported in middle-aged women mostly with complaints of abdominal pain. Electron microscopy or immunohistochemistry are needed to make a differential diagnosis towards other multicystic lesions, such as peritoneal cystic lymphangioma. Although multicystic mesothelial proliferations of the peritoneum have often been regarded as benign neoplasms, the true nature - neoplastic or hyperplastic - of these lesions still remains greatly elusive. Therefore, we believe that the unbinding term benign multicystic mesothelial proliferation (first used with regard to the unique hitherto reported case arisen in the pleural cavity) should be considered at present more appropriate to indicate even these peritoneal lesions.

Original languageEnglish
Pages (from-to)575-583
Number of pages9
JournalHistology and Histopathology
Volume6
Issue number4
Publication statusPublished - 1991

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Peritoneum
Electron Microscopy
Immunohistochemistry
Electrons
Cystic Lymphangioma
Pleural Cavity
Mesothelioma
Mucins
Abdomen
Abdominal Pain
Differential Diagnosis
Coloring Agents
Pain
Neoplasms

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine
  • Histology
  • Cell Biology

Cite this

Benign multicystic mesothelial proliferation of the peritoneum : Immunohistochemical and electron microscopical study of a case and review of the literature. / Pelosi, G.; Zannoni, M.; Caprioli, F.; Faccincani, L.; Battistoni, M. G.; Balercia, G.; Bontempini, L.

In: Histology and Histopathology, Vol. 6, No. 4, 1991, p. 575-583.

Research output: Contribution to journalArticle

Pelosi, G. ; Zannoni, M. ; Caprioli, F. ; Faccincani, L. ; Battistoni, M. G. ; Balercia, G. ; Bontempini, L. / Benign multicystic mesothelial proliferation of the peritoneum : Immunohistochemical and electron microscopical study of a case and review of the literature. In: Histology and Histopathology. 1991 ; Vol. 6, No. 4. pp. 575-583.
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