Benzodiazepine receptor antagonists reverse the effect of diazepam on plasma corticosterone in stress rats

A. Bizzi, M. R. Ricci, E. Veneroni, M. Amato, S. Garattini

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this work has been to investigate the mechanism by which diazepam counteracts the plasma corticosterone rise induced by stress in rats. This effect is reversed by pretreatment with RO151788 and CGS8216. This observation suggests that the effect is mediated by benzodiazepine-specific receptors in brain.

Original languageEnglish
Pages (from-to)134-135
Number of pages2
JournalJournal of Pharmacy and Pharmacology
Volume36
Issue number2
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science

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