Benzodiazepine receptors': Correlation with pharmacological responses in living animals

Tiziana Mennini, Silvio Garattini

Research output: Contribution to journalArticle

Abstract

The data relating the pharmacological activities of benzodiazepines to in vivo occupancy of their receptor sites is reviewed, in the light of the complexity of evaluating pharmacodynamic parameters in living animals. Methodological problems in the measurement of in vivo receptor occupancy and species differences in benzodiazepine metabolism are considered in detail.

Original languageEnglish
Pages (from-to)2025-2035
Number of pages11
JournalLife Sciences
Volume31
Issue number19
DOIs
Publication statusPublished - Nov 8 1982

ASJC Scopus subject areas

  • Pharmacology

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