Best practices for the Management of Local-regional Recurrent Chordoma. A Position Paper by the Chordoma Global Consensus Group

Silvia Stacchiotti, Alessandro Gronchi, Piero Fossati, T Akiyama, Claire Alapetite, M Baumann, J. Y. Blay, Stephanie Bolle, Stefano Boriani, P. Bruzzi, Rodolfo Capanna, A Caraceni, Roberto Casadei, Vittoria Colia, J. Debus, T. F. Delaney, A Desai, P Dileo, Sander D. Dijkstra, Francesco DogliettoAdrienne M. Flanagan, S Froelich, P A Gardner, Hans Gelderblom, Ziya L. Gokaslan, R Haas, C Heery, Nadia Hindi, Peter Hohenberger, Francis J. Hornicek, Reiko Imai, L. Jeys, R. L. Jones, Bernd Kasper, A Kawai, Marco Krengli, Andreas Leithner, I Logowska, Javier Martin-Broto, Diego Mazzatenta, Carlo Morosi, Piero Nicolai, Ole Jacob Norum, S Patel, N. Penel, Piero Picci, S. Pilotti, Stefano Radaelli, Francesca Ricchini, Piotr Rutkowski, Susanne Scheipl, C Sen, Elena Tamborini, K A Thornton, B Timmermann, V. Torri, Per Ulf Tunn, Mathias Uhl, Y Yamada, Damien C. Weber, Daniel Vanel, Peter Pal Varga, Carmen Vleggeert-Lankamp, Paolo Giovanni Casali, Josh Sommer

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Chordomas are rare, malignant bone tumors of the skull-base and axial skeleton. Until recently, there was no consensus among experts regarding appropriate clinical management of chordoma, resulting in inconsistent care and suboptimal outcomes for many patients. To address this shortcoming, the European Society of Medical Oncology (ESMO) and the Chordoma Foundation, the global chordoma patient advocacy group, convened a multi-disciplinary group of chordoma specialists to define by consensus evidence-based best practices for the optimal approach to chordoma. In January 2015, the first recommendations of this group were published, covering the management of primary and metastatic chordomas. Additional evidence and further discussion were needed to develop recommendations about the management of local-regional failures. Thus, ESMO and CF convened a second consensus group meeting in November 2015 to address the treatment of locally relapsed chordoma. This meeting involved over 60 specialists from Europe, the United States and Japan with expertise in treatment of patients with chordoma. The consensus achieved during that meeting is the subject of the present publication and complements the recommendations of the first position paper.
Original languageEnglish
Pages (from-to)1230-1242
Number of pages13
JournalAnnals of Oncology
Volume28
Issue number6
DOIs
Publication statusPublished - Feb 9 2017

Fingerprint

Chordoma
Practice Management
Practice Guidelines
Consensus
Medical Oncology
Patient Advocacy
Group Processes
Evidence-Based Practice
Skull Base
Skeleton
Japan
Bone and Bones

Keywords

  • chemotherapy
  • chordoma
  • radiotherapy
  • relapse
  • sarcoma
  • surgery

Cite this

Stacchiotti, S., Gronchi, A., Fossati, P., Akiyama, T., Alapetite, C., Baumann, M., ... Sommer, J. (2017). Best practices for the Management of Local-regional Recurrent Chordoma. A Position Paper by the Chordoma Global Consensus Group. Annals of Oncology, 28(6), 1230-1242. https://doi.org/10.1093/annonc/mdx054

Best practices for the Management of Local-regional Recurrent Chordoma. A Position Paper by the Chordoma Global Consensus Group. / Stacchiotti, Silvia; Gronchi, Alessandro; Fossati, Piero; Akiyama, T; Alapetite, Claire; Baumann, M; Blay, J. Y.; Bolle, Stephanie; Boriani, Stefano; Bruzzi, P.; Capanna, Rodolfo; Caraceni, A; Casadei, Roberto; Colia, Vittoria; Debus, J.; Delaney, T. F.; Desai, A; Dileo, P; Dijkstra, Sander D.; Doglietto, Francesco; Flanagan, Adrienne M.; Froelich, S; Gardner, P A; Gelderblom, Hans; Gokaslan, Ziya L.; Haas, R; Heery, C; Hindi, Nadia; Hohenberger, Peter; Hornicek, Francis J.; Imai, Reiko; Jeys, L.; Jones, R. L.; Kasper, Bernd; Kawai, A; Krengli, Marco; Leithner, Andreas; Logowska, I; Martin-Broto, Javier; Mazzatenta, Diego; Morosi, Carlo; Nicolai, Piero; Norum, Ole Jacob; Patel, S; Penel, N.; Picci, Piero; Pilotti, S.; Radaelli, Stefano; Ricchini, Francesca; Rutkowski, Piotr; Scheipl, Susanne; Sen, C; Tamborini, Elena; Thornton, K A; Timmermann, B; Torri, V.; Tunn, Per Ulf; Uhl, Mathias; Yamada, Y; Weber, Damien C.; Vanel, Daniel; Varga, Peter Pal; Vleggeert-Lankamp, Carmen; Casali, Paolo Giovanni; Sommer, Josh.

In: Annals of Oncology, Vol. 28, No. 6, 09.02.2017, p. 1230-1242.

Research output: Contribution to journalArticle

Stacchiotti, S, Gronchi, A, Fossati, P, Akiyama, T, Alapetite, C, Baumann, M, Blay, JY, Bolle, S, Boriani, S, Bruzzi, P, Capanna, R, Caraceni, A, Casadei, R, Colia, V, Debus, J, Delaney, TF, Desai, A, Dileo, P, Dijkstra, SD, Doglietto, F, Flanagan, AM, Froelich, S, Gardner, PA, Gelderblom, H, Gokaslan, ZL, Haas, R, Heery, C, Hindi, N, Hohenberger, P, Hornicek, FJ, Imai, R, Jeys, L, Jones, RL, Kasper, B, Kawai, A, Krengli, M, Leithner, A, Logowska, I, Martin-Broto, J, Mazzatenta, D, Morosi, C, Nicolai, P, Norum, OJ, Patel, S, Penel, N, Picci, P, Pilotti, S, Radaelli, S, Ricchini, F, Rutkowski, P, Scheipl, S, Sen, C, Tamborini, E, Thornton, KA, Timmermann, B, Torri, V, Tunn, PU, Uhl, M, Yamada, Y, Weber, DC, Vanel, D, Varga, PP, Vleggeert-Lankamp, C, Casali, PG & Sommer, J 2017, 'Best practices for the Management of Local-regional Recurrent Chordoma. A Position Paper by the Chordoma Global Consensus Group', Annals of Oncology, vol. 28, no. 6, pp. 1230-1242. https://doi.org/10.1093/annonc/mdx054
Stacchiotti, Silvia ; Gronchi, Alessandro ; Fossati, Piero ; Akiyama, T ; Alapetite, Claire ; Baumann, M ; Blay, J. Y. ; Bolle, Stephanie ; Boriani, Stefano ; Bruzzi, P. ; Capanna, Rodolfo ; Caraceni, A ; Casadei, Roberto ; Colia, Vittoria ; Debus, J. ; Delaney, T. F. ; Desai, A ; Dileo, P ; Dijkstra, Sander D. ; Doglietto, Francesco ; Flanagan, Adrienne M. ; Froelich, S ; Gardner, P A ; Gelderblom, Hans ; Gokaslan, Ziya L. ; Haas, R ; Heery, C ; Hindi, Nadia ; Hohenberger, Peter ; Hornicek, Francis J. ; Imai, Reiko ; Jeys, L. ; Jones, R. L. ; Kasper, Bernd ; Kawai, A ; Krengli, Marco ; Leithner, Andreas ; Logowska, I ; Martin-Broto, Javier ; Mazzatenta, Diego ; Morosi, Carlo ; Nicolai, Piero ; Norum, Ole Jacob ; Patel, S ; Penel, N. ; Picci, Piero ; Pilotti, S. ; Radaelli, Stefano ; Ricchini, Francesca ; Rutkowski, Piotr ; Scheipl, Susanne ; Sen, C ; Tamborini, Elena ; Thornton, K A ; Timmermann, B ; Torri, V. ; Tunn, Per Ulf ; Uhl, Mathias ; Yamada, Y ; Weber, Damien C. ; Vanel, Daniel ; Varga, Peter Pal ; Vleggeert-Lankamp, Carmen ; Casali, Paolo Giovanni ; Sommer, Josh. / Best practices for the Management of Local-regional Recurrent Chordoma. A Position Paper by the Chordoma Global Consensus Group. In: Annals of Oncology. 2017 ; Vol. 28, No. 6. pp. 1230-1242.
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AU - Stacchiotti, Silvia

AU - Gronchi, Alessandro

AU - Fossati, Piero

AU - Akiyama, T

AU - Alapetite, Claire

AU - Baumann, M

AU - Blay, J. Y.

AU - Bolle, Stephanie

AU - Boriani, Stefano

AU - Bruzzi, P.

AU - Capanna, Rodolfo

AU - Caraceni, A

AU - Casadei, Roberto

AU - Colia, Vittoria

AU - Debus, J.

AU - Delaney, T. F.

AU - Desai, A

AU - Dileo, P

AU - Dijkstra, Sander D.

AU - Doglietto, Francesco

AU - Flanagan, Adrienne M.

AU - Froelich, S

AU - Gardner, P A

AU - Gelderblom, Hans

AU - Gokaslan, Ziya L.

AU - Haas, R

AU - Heery, C

AU - Hindi, Nadia

AU - Hohenberger, Peter

AU - Hornicek, Francis J.

AU - Imai, Reiko

AU - Jeys, L.

AU - Jones, R. L.

AU - Kasper, Bernd

AU - Kawai, A

AU - Krengli, Marco

AU - Leithner, Andreas

AU - Logowska, I

AU - Martin-Broto, Javier

AU - Mazzatenta, Diego

AU - Morosi, Carlo

AU - Nicolai, Piero

AU - Norum, Ole Jacob

AU - Patel, S

AU - Penel, N.

AU - Picci, Piero

AU - Pilotti, S.

AU - Radaelli, Stefano

AU - Ricchini, Francesca

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AU - Scheipl, Susanne

AU - Sen, C

AU - Tamborini, Elena

AU - Thornton, K A

AU - Timmermann, B

AU - Torri, V.

AU - Tunn, Per Ulf

AU - Uhl, Mathias

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AU - Vanel, Daniel

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AU - Casali, Paolo Giovanni

AU - Sommer, Josh

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KW - chordoma

KW - radiotherapy

KW - relapse

KW - sarcoma

KW - surgery

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