Beta-Adrenoceptor Antagonists and Antianginal Drugs

Research output: Contribution to journalArticle

Abstract

The Side Effects of Drugs Annuals is a series of volumes in which the adverse effects of drugs and adverse reactions to them are surveyed. The series supplements the contents of Meyler's Side Effects of Drugs: the International Encyclopedia of Adverse Drug Reactions and Interactions. This review of the 2014 publications on beta-adrenoceptor antagonists and antianginal drugs covers beta-adrenoceptor antagonists (esmolol, levobunolol, nebivolol, and propranolol, timolol), the potassium channel activator nicorandil, and calcium channel blockers (amlodipine, nicardipine, nifedipine, and verapamil). Highlights include reports of the maternal and pregnancy risk and hepatorenal syndrome after beta-blocker exposure, delirium associated with the use of esmolol, severe bradyarrhythmias with levobunolol and nebivolol, metabolism and electrolyte imbalance in patient treated with nebivolol and propranolol, dermatological effects with the use of propranolol, light-headedness with timolol. Moreover, the review reports cases of methaemoglobinaemia and corneal ulceration with nicorandil. Cases of breast cancer, gingival overgrowth, pulmonary edema, intestinal obstruction, severe hypotension, overdose and poisoning with the use of calcium channel blockers (amlodipine, nifedipine and verapamil) have been described.

Original languageEnglish
JournalSide Effects of Drugs Annual
DOIs
Publication statusAccepted/In press - 2015

Fingerprint

Nebivolol
Drug-Related Side Effects and Adverse Reactions
Adrenergic Receptors
Levobunolol
Propranolol
Nicorandil
Timolol
Amlodipine
Calcium Channel Blockers
Nifedipine
Verapamil
Pharmaceutical Preparations
Gingival Overgrowth
Encyclopedias
Hepatorenal Syndrome
Methemoglobinemia
Nicardipine
Delirium
Intestinal Obstruction
Potassium Channels

Keywords

  • Adverse reactions
  • Amlodipine
  • Antianginal drugs
  • Beta-adrenoceptor antagonists
  • Calcium channel blockers
  • Esmolol
  • Levobunolol
  • Nevibolol
  • Nicardipine
  • Nicorandil
  • Nifedipine
  • Propranolol
  • Timolol
  • Verapamil

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Drug guides

Cite this

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title = "Beta-Adrenoceptor Antagonists and Antianginal Drugs",
abstract = "The Side Effects of Drugs Annuals is a series of volumes in which the adverse effects of drugs and adverse reactions to them are surveyed. The series supplements the contents of Meyler's Side Effects of Drugs: the International Encyclopedia of Adverse Drug Reactions and Interactions. This review of the 2014 publications on beta-adrenoceptor antagonists and antianginal drugs covers beta-adrenoceptor antagonists (esmolol, levobunolol, nebivolol, and propranolol, timolol), the potassium channel activator nicorandil, and calcium channel blockers (amlodipine, nicardipine, nifedipine, and verapamil). Highlights include reports of the maternal and pregnancy risk and hepatorenal syndrome after beta-blocker exposure, delirium associated with the use of esmolol, severe bradyarrhythmias with levobunolol and nebivolol, metabolism and electrolyte imbalance in patient treated with nebivolol and propranolol, dermatological effects with the use of propranolol, light-headedness with timolol. Moreover, the review reports cases of methaemoglobinaemia and corneal ulceration with nicorandil. Cases of breast cancer, gingival overgrowth, pulmonary edema, intestinal obstruction, severe hypotension, overdose and poisoning with the use of calcium channel blockers (amlodipine, nifedipine and verapamil) have been described.",
keywords = "Adverse reactions, Amlodipine, Antianginal drugs, Beta-adrenoceptor antagonists, Calcium channel blockers, Esmolol, Levobunolol, Nevibolol, Nicardipine, Nicorandil, Nifedipine, Propranolol, Timolol, Verapamil",
author = "A. Nobili and L. Pasina and R. Latini",
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language = "English",
journal = "Side Effects of Drugs Annual",
issn = "0378-6080",
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AU - Nobili, A.

AU - Pasina, L.

AU - Latini, R.

PY - 2015

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