Beta-adrenoceptor antagonists and antianginal drugs

Research output: Contribution to journalArticlepeer-review

Abstract

The Side Effects of Drugs Annuals form a series of volumes in which the adverse effects of drugs and adverse reactions to them are surveyed. The series supplements the contents of Meyler's Side Effects of Drugs: the International Encyclopedia of Adverse Drug Reactions and Interactions. This review of the 2011 publications on beta-adrenoceptor antagonists and antianginal drugs covers labetalol, metoprolol, and propranolol, the potassium channel activator nicorandil, glyceryl trinitrate (nitroglycerin), and calcium channel blockers (amlodipine, diltiazem, felodipine, nicardipine, nifedipine, and verapamil). Highlights include reports of paracentesis-induced circulatory dysfunction in patients with liver disease taking beta-blockers, posterior ischemic optic neuropathy in two patients who took overdoses of metoprolol plus verapamil, hypoglycemia due to propranolol in children with infantile hemangiomas, penile ulceration in men taking nicorandil, a rare event, paradoxical hypertension in a woman taking glyceryl trinitrate, also rare, and the use of intravenous lipid emulsion to treat severe toxicity from calcium channel blockers.

Original languageEnglish
Pages (from-to)351-357
Number of pages7
JournalSide Effects of Drugs Annual
Volume35
DOIs
Publication statusPublished - 2014

Keywords

  • Adverse reactions
  • Amlodipine
  • Antianginal drugs
  • Beta-adrenoceptor antagonists
  • Calcium channel blockers
  • Diltiazem
  • Felodipine
  • Glyceryl trinitrate
  • Labetalol
  • Metoprolol
  • Nicardipine
  • Nicorandil
  • Nifedipine
  • Nitroglycerin
  • Propranolol
  • Verapamil

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Drug guides

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