Bi-directional activation of inflammation and coagulation in septic neonates

Antonio Del Vecchio; Mauro Stronati; Caterina Franco; Robert D. Christensen

doi:10.1016/S0378-3782(14)70008-8

Bi-directional activation of inflammation and coagulation in septic neonates

Antonio Del Vecchio, Mauro Stronati, Caterina Franco, Robert D. Christensen

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Neonatal sepsis is frequently accompanied by significant and sometimes life-threatening coagulopathy. More complete understanding is needed of the molecular and cellular mechanisms underlying the interaction of the inflammatory and hemostatic systems. Such information may help focus future studies toward novel ways to improve the outcome of neonates who develop septic coagulopathy.

Original language	English
Journal	Early Human Development
Volume	90
Issue number	SUPPL.1
DOIs	https://doi.org/10.1016/S0378-3782(14)70008-8
Publication status	Published - 2014

Keywords

Coagulation
Inflammation
Inflammatory cytokines
Neonate
Sepsis

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynaecology
Medicine(all)

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10.1016/S0378-3782(14)70008-8

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Cite this

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title = "Bi-directional activation of inflammation and coagulation in septic neonates",

abstract = "Neonatal sepsis is frequently accompanied by significant and sometimes life-threatening coagulopathy. More complete understanding is needed of the molecular and cellular mechanisms underlying the interaction of the inflammatory and hemostatic systems. Such information may help focus future studies toward novel ways to improve the outcome of neonates who develop septic coagulopathy.",

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KW - Inflammation

KW - Inflammatory cytokines

KW - Neonate

KW - Sepsis

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