Bihemispheric stimulation over left and right inferior frontal region enhances recovery from apraxia of speech in chronic aphasia

Paola Marangolo, Valentina Fiori, Susanna Cipollari, Serena Campana, Carmelina Razzano, Margherita Di Paola, Giacomo Koch, Carlo Caltagirone

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Several studies have already shown that transcranial direct current stimulation (tDCS) is a useful tool for enhancing recovery in aphasia. However, all tDCS studies have previously investigated the effects using unihemisperic stimulation. No reports to date have examined the role of bihemispheric tDCS on aphasia recovery. Here, eight aphasic persons with apraxia of speech underwent intensive language therapy in two different conditions: real bihemispheric anodic ipsilesional stimulation over the left Broca's area and cathodic contralesional stimulation over the right homologue of Broca's area, and a sham condition. In both conditions, patients underwent concurrent language therapy for their apraxia of speech. The language treatment lasted 10 days (Monday to Friday, then weekend off, then Monday to Friday). There was a 14-day intersession interval between the real and the sham conditions. In all patients, language measures were collected before (T0), at the end of (T10) and 1 week after the end of (F/U) treatment. Results showed that after simultaneous excitatory stimulation to the left frontal hemisphere and inhibitory stimulation to the right frontal hemisphere regions, patients exhibited a significant recovery not only in terms of better accuracy and speed in articulating the treated stimuli but also in other language tasks (picture description, noun and verb naming, word repetition, word reading) which persisted in the follow-up session. Taken together, these data suggest that bihemispheric anodic ipsilesional and cathodic contralesional stimulation in chronic aphasia patients may affect the treated function, resulting in a positive influence on different language tasks.

Original languageEnglish
Pages (from-to)3370-3377
Number of pages8
JournalEuropean Journal of Neuroscience
Volume38
Issue number9
DOIs
Publication statusPublished - Nov 2013

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Apraxias
Aphasia
Language
Language Therapy
Reading
Therapeutics
Transcranial Direct Current Stimulation
Broca Area

Keywords

  • Brain stimulation
  • Language articulation
  • Speech therapy
  • Transcranial stimulation

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Bihemispheric stimulation over left and right inferior frontal region enhances recovery from apraxia of speech in chronic aphasia. / Marangolo, Paola; Fiori, Valentina; Cipollari, Susanna; Campana, Serena; Razzano, Carmelina; Di Paola, Margherita; Koch, Giacomo; Caltagirone, Carlo.

In: European Journal of Neuroscience, Vol. 38, No. 9, 11.2013, p. 3370-3377.

Research output: Contribution to journalArticle

Marangolo, Paola ; Fiori, Valentina ; Cipollari, Susanna ; Campana, Serena ; Razzano, Carmelina ; Di Paola, Margherita ; Koch, Giacomo ; Caltagirone, Carlo. / Bihemispheric stimulation over left and right inferior frontal region enhances recovery from apraxia of speech in chronic aphasia. In: European Journal of Neuroscience. 2013 ; Vol. 38, No. 9. pp. 3370-3377.
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