Bilateral and unilateral adrenal incidentalomas: biochemical and clinical characteristics.

V. Morelli, S. Palmieri, A. S. Salcuni, C. Eller-Vainicher, E. Cairoli, V. Zhukouskaya, A. Scillitani, P. Beck-Peccoz, I. Chiodini

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Abstract

The possible different prevalence of arterial hypertension (AH), type 2 diabetes mellitus (T2DM), dyslipidaemia (DL) and vertebral fractures (FX) between patients with bilateral and unilateral adrenal incidentalomas (BAI and UAI, respectively) with and without subclinical hypercortisolism (SH) is unknown. In this study we compared the prevalence of AH, T2DM, DL and FX in BAI and UAI patients in relation to SH. Prospective study. In 175 UAI and 38 BAI patients, we evaluated BMI, spinal and femoral bone mineral density (LS and FN BMD, respectively) and the presence of AH, T2DM, DL and FX. SH was diagnosed in the presence of 2 of the following: urinary free cortisol levels >193 nmol/24 h, serum cortisol levels after 1 mg dexamethasone suppression test >83 nmol/l or ACTH levels

Original languageEnglish
Pages (from-to)235-241
Number of pages7
JournalEuropean Journal of Endocrinology
Volume168
Issue number2
DOIs
Publication statusPublished - Feb 2013

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ASJC Scopus subject areas

  • Medicine(all)

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