Bilateral centrotemporal spikes triggered by blinking: an unusual form of sensory input with related cortical EEG activity

R. Vetrugno, S. Meletti, G. Plazzi, A. Posar, M. Santucci, P. Giovanardi Rossi, E. Lugaresi, R. Liguori

Research output: Contribution to journalArticle

Abstract

Objective: To investigate the morphology, scalp topography and temporal relationship with orbicularis oculi muscle contraction of bilateral blink related spikes (BRS) in a 7-year-old boy with chromosomopathy, mild mental retardation and left spontaneous centrotemporal spikes (SS). Methods: The patient underwent video-polygraphic recordings with off-line analysis of SS and BRS by means of spike-averaging and orbicularis oculi contraction-locked averaging techniques respectively. EEG activity related to reflex blinking (evoked by glabellar tapping) was also studied.Results: SS and BRS presented the same morphology, characterised by four peaks (P1, N1, P2, N2). SS were located over the left centroparietal regions, while BRS were placed over both left and right centrotemporoparietal regions and constantly followed the contraction of orbicularis oculi with overlapping peak latencies over C3 and C4 electrodes (P1 72 ms; N1 115 ms; P2 164 ms; N2 236 ms). Reflex blinking evoked a small waveform with the same features as BRS. Conclusions: Our findings suggest that both involuntary and reflex blinking can act as a form of sensory stimulation probably engaging similar nervous pathways and cortical sources in generating EEG abnormalities: the trigeminal system. Copyright (C) 1999 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)1995-1999
Number of pages5
JournalClinical Neurophysiology
Volume110
Issue number11
DOIs
Publication statusPublished - Nov 1 1999

Keywords

  • Blinking
  • Centrotemporal spikes
  • Tapping
  • Trigeminal system

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Sensory Systems
  • Physiology (medical)

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