Bilateral choanal atresia and endoscopic surgery: A chance for charge patients

Maria Baldovin, Diego Cazzador, Claudia Zanotti, Giuliana Frasson, Athanasios Saratziotis, Fabio Pagella, Stefano Pelucchi, Enzo Emanuelli

Research output: Contribution to journalArticlepeer-review


Bilateral choanal atresia (CA) is a rare congenital malformation frequently associated with other anomalies. CHARGE association is closely linked to bilateral CA. The aim of this study was to describe the outcomes of the endoscopic repair in bilateral CA, and to assess the role of postoperative nasal stenting in two cohorts of CHARGE-associated and non-syndromic CA. Thirty-nine children were retrospectively analyzed (16 patients had CHARGE-associated CA). The rate of postoperative neochoanal restenosis was 31.3% in the CHARGE population, and 47.8% in the non-syndromic CA cohort. Data on postoperative synechiae and granulation tissue formation, need for endonasal toilette and dilation procedures, and number of procedures per patient were presented. Stent positioning led to a higher number of postoperative dilation procedures per patient in the non-syndromic cohort (p = 0.018), and to a higher rate of restenosis both in the CHARGE-associated, and non-syndromic CA populations. Children with CHARGE-associated and non-syndromic bilateral CA benefitted from endonasal endoscopic CA correction. The postoperative application of an endonasal stent should be carefully evaluated.

Original languageEnglish
Article number2951
JournalJournal of Clinical Medicine
Issue number13
Publication statusPublished - Jul 1 2021


  • Bilateral
  • CHARGE association
  • Choanal atresia
  • Congenital malfor-mations
  • Endoscopic surgery
  • Nasal obstruction
  • Neonatal and pediatric airway disorders
  • Postoperative outcomes
  • Restenosis
  • Stent

ASJC Scopus subject areas

  • Medicine(all)


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