Bilateral choroidal metastasis from adenoid cystic carcinoma of the submandibular salivary gland

Daniela Bacherini, Marco Pellegrini, Giulio Vicini, Cristina Nicolosi, Giulia Pieretti, Lorenzo Vannozzi, Stanislao Rizzo, Cinzia Mazzini, Fabrizio Giansanti

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: A case of bilateral choroidal metastasis from an adenoid cystic carcinoma of the submandibular gland is described. Case description: A 45-years-old woman with a history of metastatic adenoid cystic carcinoma presented with visual impairment in both eyes. Fundus images showed bilateral creamy-white choroidal masses. Optical coherence tomography revealed subretinal fluid with high reflective speckles and a “lumpy bumpy” anterior contour of the lesions. Fluorescein angiography showed a hypofluorescent pattern of the lesions in early arterial phases, and progressive late hyperfluorescence. A diagnosis of bilateral choroidal metastasis from adenoid cystic carcinoma was made. The patient was advised to underwent palliative chemotherapy, but she expired a few weeks after the diagnosis. Conclusion: Salivary gland carcinoma rarely metastasizes to the choroid, with few cases described in literature. In patients with a history of salivary glands tumor the possibility of choroidal metastatization should always be considered.

Original languageEnglish
JournalEuropean Journal of Ophthalmology
DOIs
Publication statusAccepted/In press - 2020

Keywords

  • Adenoid cystic carcinoma
  • choroidal metastasis
  • OCT
  • submandibular salivary gland carcinoma

ASJC Scopus subject areas

  • Ophthalmology

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