Bilateral consecutive rupture of the quadriceps tendon in a man with BstUI polymorphism of the COL5A1 gene

Umile Giuseppe Longo, Vito Fazio, Maria Luana Poeta, Carla Rabitti, Francesco Franceschi, Nicola Maffulli, Vincenzo Denaro

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

A genetic component has been implicated in tendinopathies involving tendon rupture. Type V collagen, a quantitatively minor fibrillar collagen which forms heterotypic fibrils with type I collagen, plays a role in the regulation of the size and configuration of fibrils of the much more abundant component type I collagen. To date, no data on the genetic component of bilateral rupture of the quadriceps tendon have been reported. We describe the presence of BstUI polymorphism of the COL5A1 gene in a man with bilateral rupture of the quadriceps tendon. The COL5A1 (the variant rs12722, BstUI RFLP) can be a candidate gene associated with the development of bilateral quadriceps tendon rupture.

Original languageEnglish
Pages (from-to)514-518
Number of pages5
JournalKnee Surgery, Sports Traumatology, Arthroscopy
Volume18
Issue number4
DOIs
Publication statusPublished - Apr 2010

Fingerprint

Tendons
Rupture
Collagen Type I
Genes
Collagen Type V
Fibrillar Collagens
Tendinopathy
Restriction Fragment Length Polymorphisms

Keywords

  • Gene
  • Genetics
  • Polymorphism
  • Sports
  • Tendinopathy
  • Tendon

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

Cite this

Bilateral consecutive rupture of the quadriceps tendon in a man with BstUI polymorphism of the COL5A1 gene. / Longo, Umile Giuseppe; Fazio, Vito; Poeta, Maria Luana; Rabitti, Carla; Franceschi, Francesco; Maffulli, Nicola; Denaro, Vincenzo.

In: Knee Surgery, Sports Traumatology, Arthroscopy, Vol. 18, No. 4, 04.2010, p. 514-518.

Research output: Contribution to journalArticle

Longo, Umile Giuseppe ; Fazio, Vito ; Poeta, Maria Luana ; Rabitti, Carla ; Franceschi, Francesco ; Maffulli, Nicola ; Denaro, Vincenzo. / Bilateral consecutive rupture of the quadriceps tendon in a man with BstUI polymorphism of the COL5A1 gene. In: Knee Surgery, Sports Traumatology, Arthroscopy. 2010 ; Vol. 18, No. 4. pp. 514-518.
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