Bilateral Internal Carotid Artery Segmental Agenesis: Embryology, Common Collateral Pathways, Clinical Presentation, and Clinical Importance of a Rare Condition

Andrea M. Alexandre, Emiliano Visconti, Chiara Schiarelli, Paolo Frassanito, Alessandro Pedicelli

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background Bilateral segmental agenesis of the internal carotid artery is a rare congenital anomaly. We present a case of bilateral internal carotid artery segmental agenesis in an asymptomatic 18-year-old man. Embryology, common collateral pathways, clinical presentation, and clinical importance of this condition are discussed. According to our review of the literature, this report is the first to describe bilateral internal carotid artery segmental agenesis in a patient studied with magnetic resonance imaging, computed tomography, Doppler ultrasonography, and digital subtraction angiography. Case Description An 18-year-old man presented to our hospital complaining of occasional mild headaches. Neurologic examination was unremarkable. Imaging findings consisted of bilateral segmental agenesis of the internal carotid arteries. Conclusion Bilateral segmental agenesis of internal carotid artery may be completely asymptomatic and harmless, but associated conditions, such as cerebral aneurysms or abnormal collateral circulation, should alert clinicians to the possibilities of subarachnoid hemorrhage or cerebral ischemia.

Original languageEnglish
Pages (from-to)620
Number of pages1
JournalWorld Neurosurgery
Volume95
DOIs
Publication statusPublished - Nov 1 2016
Externally publishedYes

Fingerprint

Critical Pathways
Embryology
Internal Carotid Artery
Doppler Ultrasonography
Collateral Circulation
Digital Subtraction Angiography
Neurologic Examination
Intracranial Aneurysm
Subarachnoid Hemorrhage
Brain Ischemia
Headache
Tomography
Magnetic Resonance Imaging

Keywords

  • Absence of the internal carotid artery
  • Doppler ultrasonography
  • Internal carotid artery
  • Internal carotid artery hypoplasia
  • Internal carotid artery malformations
  • Internal carotid artery segmental agenesis
  • Rete mirabile

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Bilateral Internal Carotid Artery Segmental Agenesis : Embryology, Common Collateral Pathways, Clinical Presentation, and Clinical Importance of a Rare Condition. / Alexandre, Andrea M.; Visconti, Emiliano; Schiarelli, Chiara; Frassanito, Paolo; Pedicelli, Alessandro.

In: World Neurosurgery, Vol. 95, 01.11.2016, p. 620.

Research output: Contribution to journalArticle

Alexandre, Andrea M. ; Visconti, Emiliano ; Schiarelli, Chiara ; Frassanito, Paolo ; Pedicelli, Alessandro. / Bilateral Internal Carotid Artery Segmental Agenesis : Embryology, Common Collateral Pathways, Clinical Presentation, and Clinical Importance of a Rare Condition. In: World Neurosurgery. 2016 ; Vol. 95. pp. 620.
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