Translated title of the contribution: Bile secretion

N. Dioguardi, C. Di Padova, M. Podda

Research output: Contribution to journalArticlepeer-review


The canaliculus is the primary site for the formation of bile. Here, active secretion of bile acids creates an osmotic gradient between bile and blood, crossed passively by water and solutes. Numerous experimental data point to the existence of a canalicular bile fraction that is independent of the active transport of bile acids, and related to active sodium secretion. The bile ducts are not merely conduits for the passage of bile, but can also change its volume and composition by means of both absorption and secretion. Nervous, vascular, hormonal and pharmacological factors serve to modify bile secretion. In most cases, however, their mechanism of action is virtually unknown.

Translated title of the contributionBile secretion
Original languageItalian
Pages (from-to)1-19
Number of pages19
JournalMinerva Medica
Issue number1
Publication statusPublished - 1975

ASJC Scopus subject areas

  • Medicine(all)


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