Il bypass bilio-intestinale nel trattamento dell'obesità grave. Nostra esperienza su 23 pazienti

Translated title of the contribution: Biliary-intestinal bypass in the treatment of severe obesity: Personal experience on 23 patients

G. Galati, L. Izzo, B. Binda, A. De Cesare, E. Fiori, M. Bononi, L. Masoni, M. Badiali

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background. The aim of this study was to determine the efficacy and safety of biliary-intestinal bypass in severely obese subjects (Body Mass Index > 35). Methods. From January to December 1999, 23 patients (8 men and 15 women, mean age 36.6 years: range 20-51) affected with primary morbid obesity (BMI >40: range 40.1-64.7), in whom different attempt using conservative medicine have proved non-resolutive, underwent biliary-intestinal bypass. After the operation all the patients have been followed-up for 12 months. Results. The mean Body Mass Index was reduced to 36.9 (range 27.7-44.1) after 6 months and to 33 (range 24.9-40.1) after 12 months. Peri and postoperative mortality was zero. Excessive malabsorption was efficaciously controlled by adeguate replacement therapy. Diarrhoea, common complicance of every operation inducin malabsorbition, was reduced to 2-3 evacuation a day after 2-3 months. Conclusions. On the basis of personal experience it is underlined that biliary-intestinal bypass, as surgical treatment of morbid obesity refractory to medical therapy, is today a safe and effective operation (up to 80% of excess body weight lose); the presence of biliary-intestinal anastomosis reduces the postoperative loss of bile acids, choleretic diarrhoea and electrolytic disorders.

Original languageItalian
Pages (from-to)345-349
Number of pages5
JournalMinerva Chirurgica
Volume56
Issue number4
Publication statusPublished - 2001

Fingerprint

Jejunoileal Bypass
Morbid Obesity
Diarrhea
Body Mass Index
Cholagogues and Choleretics
Bile Acids and Salts
Therapeutics
Body Weight
Medicine
Safety
Mortality

ASJC Scopus subject areas

  • Surgery

Cite this

Galati, G., Izzo, L., Binda, B., De Cesare, A., Fiori, E., Bononi, M., ... Badiali, M. (2001). Il bypass bilio-intestinale nel trattamento dell'obesità grave. Nostra esperienza su 23 pazienti. Minerva Chirurgica, 56(4), 345-349.

Il bypass bilio-intestinale nel trattamento dell'obesità grave. Nostra esperienza su 23 pazienti. / Galati, G.; Izzo, L.; Binda, B.; De Cesare, A.; Fiori, E.; Bononi, M.; Masoni, L.; Badiali, M.

In: Minerva Chirurgica, Vol. 56, No. 4, 2001, p. 345-349.

Research output: Contribution to journalArticle

Galati, G, Izzo, L, Binda, B, De Cesare, A, Fiori, E, Bononi, M, Masoni, L & Badiali, M 2001, 'Il bypass bilio-intestinale nel trattamento dell'obesità grave. Nostra esperienza su 23 pazienti', Minerva Chirurgica, vol. 56, no. 4, pp. 345-349.
Galati, G. ; Izzo, L. ; Binda, B. ; De Cesare, A. ; Fiori, E. ; Bononi, M. ; Masoni, L. ; Badiali, M. / Il bypass bilio-intestinale nel trattamento dell'obesità grave. Nostra esperienza su 23 pazienti. In: Minerva Chirurgica. 2001 ; Vol. 56, No. 4. pp. 345-349.
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AB - Background. The aim of this study was to determine the efficacy and safety of biliary-intestinal bypass in severely obese subjects (Body Mass Index > 35). Methods. From January to December 1999, 23 patients (8 men and 15 women, mean age 36.6 years: range 20-51) affected with primary morbid obesity (BMI >40: range 40.1-64.7), in whom different attempt using conservative medicine have proved non-resolutive, underwent biliary-intestinal bypass. After the operation all the patients have been followed-up for 12 months. Results. The mean Body Mass Index was reduced to 36.9 (range 27.7-44.1) after 6 months and to 33 (range 24.9-40.1) after 12 months. Peri and postoperative mortality was zero. Excessive malabsorption was efficaciously controlled by adeguate replacement therapy. Diarrhoea, common complicance of every operation inducin malabsorbition, was reduced to 2-3 evacuation a day after 2-3 months. Conclusions. On the basis of personal experience it is underlined that biliary-intestinal bypass, as surgical treatment of morbid obesity refractory to medical therapy, is today a safe and effective operation (up to 80% of excess body weight lose); the presence of biliary-intestinal anastomosis reduces the postoperative loss of bile acids, choleretic diarrhoea and electrolytic disorders.

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KW - Biliary-intestinal bypass

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KW - Obesity, surgery

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