Binding of antibodies against human prealbumin to intestinal and bronchial carcinoids and to pancreatic endocrine tumours

Gianni Bussolati, Mauro Papotti, Anna Sapino

Research output: Contribution to journalArticle

Abstract

Antibodies against human prealbumin (HPA) give a strong immunoperoxidase staining of the A (glucagon) pancreatic cells and of glucagon-, insulin- and gastrin-producing pancreatic tumours. The majority of intestinal and bronchial carcinoids are also reactive. The staining may be related to presence in the C-terminal sequence of HPA of determinants in common with polypeptide (pro-) hormones.

Original languageEnglish
Pages (from-to)15-22
Number of pages8
JournalVirchows Archiv B Cell Pathology Including Molecular Pathology
Volume45
Issue number1
DOIs
Publication statusPublished - Jan 1984

Keywords

  • Carcinoids
  • Endocrine tumours
  • Immunoperoxidase
  • Pancreas
  • Pre-albumin

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medicine(all)

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