Bioavailability of a fixed combination of intramuscular diclofenac 75 mg + thiocolchicoside 4 mg single dose vs. Single components

R. Imberti, S. De Gregori, L. Rabaglia, M. Regazzi

Research output: Contribution to journalArticle

Original languageEnglish
Pages (from-to)264-267
Number of pages4
JournalMinerva Medica
Volume110
Issue number3
DOIs
Publication statusPublished - 2019

Keywords

  • diclofenac
  • diclofenac plus thiocolchicoside
  • thiocolchicoside
  • colchicine
  • adult
  • area under the curve
  • arm pain
  • AUC (0-12 h)
  • AUC (0-8 h)
  • bioequivalence
  • clinical article
  • controlled study
  • crossover procedure
  • drug bioavailability
  • drug safety
  • drug tolerability
  • elimination half-life
  • heart palpitation
  • hematoma
  • human
  • human experiment
  • injection site pain
  • Letter
  • liquid chromatography-mass spectrometry
  • maximum concentration
  • maximum plasma concentration
  • normal human
  • phase 1 clinical trial
  • randomized controlled trial
  • single drug dose
  • time to maximum plasma concentration
  • visual analog scale
  • analogs and derivatives
  • bioavailability
  • combination drug therapy
  • female
  • intramuscular drug administration
  • male
  • Adult
  • Biological Availability
  • Colchicine
  • Cross-Over Studies
  • Diclofenac
  • Drug Therapy, Combination
  • Female
  • Humans
  • Injections, Intramuscular
  • Male

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