Bioceramic materials show reduced pathological biofilm formation

Corrado Piconi, Andrei C. Ionescu, Andrea Cochis, Erica Iasi, Eugenio Brambilla, Lia Rimondini

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The aim of the present work was to assess the surface ability of three bioceramic materials (A: alumina BIOLOX® forte; B: Si3N4; C: alumina matrix composite BIOLOX® delta) to inhibit bacterial biofilm formation. For this purpose, ceramic disks at standardized roughness (Ra = 0,25 μm) were used as test materials while commercial polystyrene was considered as control. Two biofilm-producing bacterial strains (S. epidermidis ATCC14990, Escherichia coli ATCC25922) were used for experiments. The viable biomass was assessed by the metabolic MTT assay after 24h incubation. Morphological data regarding biofilms structure were obtained by scanning electron microscopy. In general, results revealed that all bioceramics materials were significantly less colonized compared to polystyrene. The degree of biofilm formation onto bioceramics ranged between about 30 to 60% less than the polystyrene control. Moreover, some differences were noticed by comparing the three bioceramics inhibition ratio: bioceramic A showed significanlty less S. epidermidis biofilm formation (p

Original languageEnglish
Title of host publicationBioceramics 26
PublisherTrans Tech Publications Ltd
Number of pages6
ISBN (Print)9783038352822
Publication statusPublished - 2015
Event26th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2014 - Barcelona, Spain
Duration: Nov 6 2014Nov 8 2014

Publication series

NameKey Engineering Materials
ISSN (Print)10139826


Other26th Symposium and Annual Meeting of the International Society for Ceramics in Medicine, ISCM 2014


  • Alumina
  • Bacteria
  • Biofilm
  • Ceramic
  • Matrix composite
  • Silica nitride

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering


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