Indagini biochimiche e cliniche su due nuovi casi italiani di eterozigosi per l'Hb G-Ferrara.

Translated title of the contribution: Biochemical and clinical studies of 2 new Italian cases of Hb G-Ferrara heterozygosis

A. Guerrasio, G. Saglio, C. Camaschella, P. G. Pich, E. Barberis, D. Del Ponte, P. Izzo

Research output: Contribution to journalArticle

Abstract

The Authors report the data concerning a family coming from Ficarolo (Rovigo). The father and one son were found hematologically healthy, but resulted carriers of Hb G-Ferrara. This is an unstable rare pigment with a replacement in the beta 57 (E-1) helicoidal position. The type and site of the mutation explain the "in vitro" molecular instability; on the other hand, this latter doesn't seem to cause any hematological disorder, even if an increased met-Hb production was found when affected blood was incubated at 37 degrees C for two hours in sterile conditions.

Translated title of the contributionBiochemical and clinical studies of 2 new Italian cases of Hb G-Ferrara heterozygosis
Original languageItalian
Pages (from-to)967-973
Number of pages7
JournalBollettino della Societa Italiana di Biologia Sperimentale
Volume55
Issue number10
Publication statusPublished - May 30 1979

ASJC Scopus subject areas

  • Medicine(all)

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    Guerrasio, A., Saglio, G., Camaschella, C., Pich, P. G., Barberis, E., Del Ponte, D., & Izzo, P. (1979). Indagini biochimiche e cliniche su due nuovi casi italiani di eterozigosi per l'Hb G-Ferrara. Bollettino della Societa Italiana di Biologia Sperimentale, 55(10), 967-973.