Markers metabolici cartilaginei

Mario Carrabba; M. G. Marrazza; G. Randisi; P. C. Sarzi-Puttini; F. Atzeni; E. E M Torchiana

Markers metabolici cartilaginei

Translated title of the contribution: Biochemical markers of cartilage

Mario Carrabba, M. G. Marrazza, G. Randisi, P. C. Sarzi-Puttini, F. Atzeni, E. E M Torchiana

IRCCS Istituto Ortopedico Galeazzi

Research output: Contribution to journal › Article › peer-review

Abstract

The Authors review the recent literature data on the biochemical markers of joint damage. In particular several metabolites are now evaluated with internationally validated methods. Among them citokines, MMPs, YKL-40, VEGF, COMP, collagen metabolites, seem the most promising for the evaluation of the articular damage. Because such markers came from different structures of the joint (bone, cartilage, synovial membrane, soft tissues of the joint, etc) or from others organs and tissues, the literature data are sometimes discordant. These studies seem more useful if such parameters, are registered as basal values and then followed in the same patients according to a planned time schedule in order to better evaluate their variations within the disease.

Translated title of the contribution	Biochemical markers of cartilage
Original language	Italian
Pages (from-to)	89-94
Number of pages	6
Journal	Progressi in Reumatologia
Volume	5
Issue number	1
Publication status	Published - 2004

ASJC Scopus subject areas

Rheumatology

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title = "Markers metabolici cartilaginei",

abstract = "The Authors review the recent literature data on the biochemical markers of joint damage. In particular several metabolites are now evaluated with internationally validated methods. Among them citokines, MMPs, YKL-40, VEGF, COMP, collagen metabolites, seem the most promising for the evaluation of the articular damage. Because such markers came from different structures of the joint (bone, cartilage, synovial membrane, soft tissues of the joint, etc) or from others organs and tissues, the literature data are sometimes discordant. These studies seem more useful if such parameters, are registered as basal values and then followed in the same patients according to a planned time schedule in order to better evaluate their variations within the disease.",

keywords = "Biochemical markers of cartilage, Metalloproteases, Vascular endothelial growth factor, YKL-40",

author = "Mario Carrabba and Marrazza, {M. G.} and G. Randisi and Sarzi-Puttini, {P. C.} and F. Atzeni and Torchiana, {E. E M}",

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AU - Carrabba, Mario

AU - Marrazza, M. G.

AU - Randisi, G.

AU - Sarzi-Puttini, P. C.

AU - Atzeni, F.

AU - Torchiana, E. E M

PY - 2004

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N2 - The Authors review the recent literature data on the biochemical markers of joint damage. In particular several metabolites are now evaluated with internationally validated methods. Among them citokines, MMPs, YKL-40, VEGF, COMP, collagen metabolites, seem the most promising for the evaluation of the articular damage. Because such markers came from different structures of the joint (bone, cartilage, synovial membrane, soft tissues of the joint, etc) or from others organs and tissues, the literature data are sometimes discordant. These studies seem more useful if such parameters, are registered as basal values and then followed in the same patients according to a planned time schedule in order to better evaluate their variations within the disease.

AB - The Authors review the recent literature data on the biochemical markers of joint damage. In particular several metabolites are now evaluated with internationally validated methods. Among them citokines, MMPs, YKL-40, VEGF, COMP, collagen metabolites, seem the most promising for the evaluation of the articular damage. Because such markers came from different structures of the joint (bone, cartilage, synovial membrane, soft tissues of the joint, etc) or from others organs and tissues, the literature data are sometimes discordant. These studies seem more useful if such parameters, are registered as basal values and then followed in the same patients according to a planned time schedule in order to better evaluate their variations within the disease.

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KW - Metalloproteases

KW - Vascular endothelial growth factor

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