Abstract
The Authors review the recent literature data on the biochemical markers of joint damage. In particular several metabolites are now evaluated with internationally validated methods. Among them citokines, MMPs, YKL-40, VEGF, COMP, collagen metabolites, seem the most promising for the evaluation of the articular damage. Because such markers came from different structures of the joint (bone, cartilage, synovial membrane, soft tissues of the joint, etc) or from others organs and tissues, the literature data are sometimes discordant. These studies seem more useful if such parameters, are registered as basal values and then followed in the same patients according to a planned time schedule in order to better evaluate their variations within the disease.
| Original language | Italian |
|---|---|
| Pages (from-to) | 89-94 |
| Number of pages | 6 |
| Journal | Progressi in Reumatologia |
| Volume | 5 |
| Issue number | 1 |
| Publication status | Published - 2004 |
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ASJC Scopus subject areas
- Rheumatology
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Markers metabolici cartilaginei. / Carrabba, Mario; Marrazza, M. G.; Randisi, G.; Sarzi-Puttini, P. C.; Atzeni, F.; Torchiana, E. E M.
In: Progressi in Reumatologia, Vol. 5, No. 1, 2004, p. 89-94.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Markers metabolici cartilaginei
AU - Carrabba, Mario
AU - Marrazza, M. G.
AU - Randisi, G.
AU - Sarzi-Puttini, P. C.
AU - Atzeni, F.
AU - Torchiana, E. E M
PY - 2004
Y1 - 2004
N2 - The Authors review the recent literature data on the biochemical markers of joint damage. In particular several metabolites are now evaluated with internationally validated methods. Among them citokines, MMPs, YKL-40, VEGF, COMP, collagen metabolites, seem the most promising for the evaluation of the articular damage. Because such markers came from different structures of the joint (bone, cartilage, synovial membrane, soft tissues of the joint, etc) or from others organs and tissues, the literature data are sometimes discordant. These studies seem more useful if such parameters, are registered as basal values and then followed in the same patients according to a planned time schedule in order to better evaluate their variations within the disease.
AB - The Authors review the recent literature data on the biochemical markers of joint damage. In particular several metabolites are now evaluated with internationally validated methods. Among them citokines, MMPs, YKL-40, VEGF, COMP, collagen metabolites, seem the most promising for the evaluation of the articular damage. Because such markers came from different structures of the joint (bone, cartilage, synovial membrane, soft tissues of the joint, etc) or from others organs and tissues, the literature data are sometimes discordant. These studies seem more useful if such parameters, are registered as basal values and then followed in the same patients according to a planned time schedule in order to better evaluate their variations within the disease.
KW - Biochemical markers of cartilage
KW - Metalloproteases
KW - Vascular endothelial growth factor
KW - YKL-40
UR - http://www.scopus.com/inward/record.url?scp=2142654374&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2142654374&partnerID=8YFLogxK
M3 - Articolo
AN - SCOPUS:2142654374
VL - 5
SP - 89
EP - 94
JO - Progressi in Reumatologia
JF - Progressi in Reumatologia
SN - 1129-8758
IS - 1
ER -