Biocompatible N-acetyl cysteine reduces graphene oxide and persists at the surface as a green radical scavenger

Valentina Palmieri; Enrique A Dalchiele; Giordano Perini; Alessandro Motta; Marco De Spirito; Robertino Zanoni; Andrea Giacomo Marrani; Massimiliano Papi

doi:10.1039/c9cc00429g

Biocompatible N-acetyl cysteine reduces graphene oxide and persists at the surface as a green radical scavenger

Valentina Palmieri, Enrique A Dalchiele, Giordano Perini, Alessandro Motta, Marco De Spirito, Robertino Zanoni, Andrea Giacomo Marrani, Massimiliano Papi

IRCCS Fondazione Policlinico Universitario A. Gemelli

Research output: Contribution to journal › Article › peer-review

Abstract

We demonstrate that N-acetyl cysteine (NAC) reduces graphene oxide (GO) at room temperature. This represents a new green method to produce reduced GO (rGO). NAC adheres to the rGO surface as demonstrated by several spectroscopy techniques and avoids GO-mediated oxidation of glutathione. This method offers new opportunities for the production of green biocompatible rGO and NAC-based therapies.

Original language	English
Pages (from-to)	4186-4189
Number of pages	4
Journal	Chemical Communications
Volume	55
Issue number	29
DOIs	https://doi.org/10.1039/c9cc00429g
Publication status	Published - Apr 4 2019

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Biocompatible N-acetyl cysteine reduces graphene oxide and persists at the surface as a green radical scavenger. / Palmieri, Valentina; Dalchiele, Enrique A; Perini, Giordano; Motta, Alessandro; De Spirito, Marco; Zanoni, Robertino; Marrani, Andrea Giacomo; Papi, Massimiliano.

In: Chemical Communications, Vol. 55, No. 29, 04.04.2019, p. 4186-4189.

Research output: Contribution to journal › Article › peer-review

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AU - Palmieri, Valentina

AU - Dalchiele, Enrique A

AU - Perini, Giordano

AU - Motta, Alessandro

AU - De Spirito, Marco

AU - Zanoni, Robertino

AU - Marrani, Andrea Giacomo

AU - Papi, Massimiliano

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AB - We demonstrate that N-acetyl cysteine (NAC) reduces graphene oxide (GO) at room temperature. This represents a new green method to produce reduced GO (rGO). NAC adheres to the rGO surface as demonstrated by several spectroscopy techniques and avoids GO-mediated oxidation of glutathione. This method offers new opportunities for the production of green biocompatible rGO and NAC-based therapies.

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Biocompatible N-acetyl cysteine reduces graphene oxide and persists at the surface as a green radical scavenger

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