Biocompatible N-acetyl cysteine reduces graphene oxide and persists at the surface as a green radical scavenger

Valentina Palmieri, Enrique A Dalchiele, Giordano Perini, Alessandro Motta, Marco De Spirito, Robertino Zanoni, Andrea Giacomo Marrani, Massimiliano Papi

Research output: Contribution to journalArticle


We demonstrate that N-acetyl cysteine (NAC) reduces graphene oxide (GO) at room temperature. This represents a new green method to produce reduced GO (rGO). NAC adheres to the rGO surface as demonstrated by several spectroscopy techniques and avoids GO-mediated oxidation of glutathione. This method offers new opportunities for the production of green biocompatible rGO and NAC-based therapies.

Original languageEnglish
Pages (from-to)4186-4189
Number of pages4
JournalChemical Communications
Issue number29
Publication statusPublished - Apr 4 2019


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