Abstract
Objectives: To evaluate feasibility, safety, and outcome of patients treated with biodegradable biliary stents for benign biliary stenosis refractory to other treatments. Methods: Between March 2011 and September 2012, ten patients (seven men, three women; age 59 ± 7 years) with recurrent cholangitis due to postsurgical biliary stricture, previous multiple unsuccessful (two to five) bilioplasties, and unsuitability for surgical/endoscopic repair underwent percutaneous implantation of a biodegradable biliary stent. Patients were followed-up clinically and with ultrasound at 1, 3 and 6 months, and then at 6-month intervals. Results: Stent implantation was always feasible. No immediate major or minor complications occurred. In all patients, 48-h cholangiographic control demonstrated optimal stent positioning and stenosis resolution. In a median follow-up time of 16.5 months (25th-75th percentiles = 11-20.25 months) no further invasive treatment was needed. Three patients experienced transient episodes of cholangitis. Neither re-stenosis nor dilatation of the biliary tree was documented during follow-up. No stent was visible at the 6-month follow-up. Conclusions: Percutaneous placement of biodegradable biliary stents represents a new option in treating benign biliary stenoses refractory to treatment with bilioplasty. This technique seems to be feasible, effective and free from major complications. Further investigations are warranted to confirm our preliminary results. Key Points: • Percutaneous biodegradable stents can be used to treat benign biliary stenosis. • They can be used in patients refractory to bilioplasty. • The procedure for insertion appears free from major complication. • Biodegradable stents may represent an alternative device to covered expandable stents.
| Original language | English |
|---|---|
| Pages (from-to) | 3304-3310 |
| Number of pages | 7 |
| Journal | European Radiology |
| Volume | 23 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Dec 2013 |
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Keywords
- Benign biliary stricture
- Biliary tree
- Bilioplasty
- Biodegradable stents
- Percutaneous biliary procedures
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Biodegradable biliary stent implantation in the treatment of benign bilioplastic-refractory biliary strictures : Preliminary experience. / Mauri, Giovanni; Michelozzi, Caterina; Melchiorre, Fabio; Poretti, Dario; Tramarin, Marco; Pedicini, Vittorio; Solbiati, Luigi; Cornalba, Gianpaolo; Sconfienza, Luca Maria.
In: European Radiology, Vol. 23, No. 12, 12.2013, p. 3304-3310.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Biodegradable biliary stent implantation in the treatment of benign bilioplastic-refractory biliary strictures
T2 - Preliminary experience
AU - Mauri, Giovanni
AU - Michelozzi, Caterina
AU - Melchiorre, Fabio
AU - Poretti, Dario
AU - Tramarin, Marco
AU - Pedicini, Vittorio
AU - Solbiati, Luigi
AU - Cornalba, Gianpaolo
AU - Sconfienza, Luca Maria
PY - 2013/12
Y1 - 2013/12
N2 - Objectives: To evaluate feasibility, safety, and outcome of patients treated with biodegradable biliary stents for benign biliary stenosis refractory to other treatments. Methods: Between March 2011 and September 2012, ten patients (seven men, three women; age 59 ± 7 years) with recurrent cholangitis due to postsurgical biliary stricture, previous multiple unsuccessful (two to five) bilioplasties, and unsuitability for surgical/endoscopic repair underwent percutaneous implantation of a biodegradable biliary stent. Patients were followed-up clinically and with ultrasound at 1, 3 and 6 months, and then at 6-month intervals. Results: Stent implantation was always feasible. No immediate major or minor complications occurred. In all patients, 48-h cholangiographic control demonstrated optimal stent positioning and stenosis resolution. In a median follow-up time of 16.5 months (25th-75th percentiles = 11-20.25 months) no further invasive treatment was needed. Three patients experienced transient episodes of cholangitis. Neither re-stenosis nor dilatation of the biliary tree was documented during follow-up. No stent was visible at the 6-month follow-up. Conclusions: Percutaneous placement of biodegradable biliary stents represents a new option in treating benign biliary stenoses refractory to treatment with bilioplasty. This technique seems to be feasible, effective and free from major complications. Further investigations are warranted to confirm our preliminary results. Key Points: • Percutaneous biodegradable stents can be used to treat benign biliary stenosis. • They can be used in patients refractory to bilioplasty. • The procedure for insertion appears free from major complication. • Biodegradable stents may represent an alternative device to covered expandable stents.
AB - Objectives: To evaluate feasibility, safety, and outcome of patients treated with biodegradable biliary stents for benign biliary stenosis refractory to other treatments. Methods: Between March 2011 and September 2012, ten patients (seven men, three women; age 59 ± 7 years) with recurrent cholangitis due to postsurgical biliary stricture, previous multiple unsuccessful (two to five) bilioplasties, and unsuitability for surgical/endoscopic repair underwent percutaneous implantation of a biodegradable biliary stent. Patients were followed-up clinically and with ultrasound at 1, 3 and 6 months, and then at 6-month intervals. Results: Stent implantation was always feasible. No immediate major or minor complications occurred. In all patients, 48-h cholangiographic control demonstrated optimal stent positioning and stenosis resolution. In a median follow-up time of 16.5 months (25th-75th percentiles = 11-20.25 months) no further invasive treatment was needed. Three patients experienced transient episodes of cholangitis. Neither re-stenosis nor dilatation of the biliary tree was documented during follow-up. No stent was visible at the 6-month follow-up. Conclusions: Percutaneous placement of biodegradable biliary stents represents a new option in treating benign biliary stenoses refractory to treatment with bilioplasty. This technique seems to be feasible, effective and free from major complications. Further investigations are warranted to confirm our preliminary results. Key Points: • Percutaneous biodegradable stents can be used to treat benign biliary stenosis. • They can be used in patients refractory to bilioplasty. • The procedure for insertion appears free from major complication. • Biodegradable stents may represent an alternative device to covered expandable stents.
KW - Benign biliary stricture
KW - Biliary tree
KW - Bilioplasty
KW - Biodegradable stents
KW - Percutaneous biliary procedures
UR - http://www.scopus.com/inward/record.url?scp=84890550282&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84890550282&partnerID=8YFLogxK
U2 - 10.1007/s00330-013-2947-2
DO - 10.1007/s00330-013-2947-2
M3 - Article
C2 - 23842947
AN - SCOPUS:84890550282
VL - 23
SP - 3304
EP - 3310
JO - European Radiology
JF - European Radiology
SN - 0938-7994
IS - 12
ER -