Bioengineering and the patch test

E. Berardesca, H. I. Maibach

Research output: Contribution to journalArticlepeer-review


Several non-invasive techniques based on different physical principles have been developed to investigate skin function and have been used for patch test assessment. In the present paper, the advantages and the defects of these methods are described in the light of the more recent data available in literature. Meanwhile, the eye and the fingers still remain the simplest method to assess skin irritancy. Bioengineering techniques could provide efficient recording systems for monitoring skin color, skin blood flow and barrier function damage, useful to the investigator rather than to the clinician.

Original languageEnglish
Pages (from-to)3-9
Number of pages7
JournalContact Dermatitis
Issue number1
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Immunology
  • Dermatology
  • Toxicology

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