Biohumoral markers as predictor of right ventricular dysfunction in AL Amyloidosis

Francesco Cappelli, Samuele Baldasseroni, Franco Bergesio, Luigi Padeletti, Paola Attanà, Alberto Moggi Pignone, Elisa Grifoni, Gabriele Ciuti, Alessia Fabbri, Francesca Tarantini, Niccolò Marchionni, Gian Franco Gensini, Federico Perfetto

Research output: Contribution to journalArticle

Abstract

Aim: In AL amyloidosis, the importance of right ventricle (RV) involvement has recently been underlined and its role in predicting prognosis has been emphasized. Little is known about the relationship between RV involvement, N-terminal pro-brain natriuretic peptide (NT-proBNP) and troponin levels. Aim of our study was to clarify the relationship between NT-proBNP and troponin and RV involvement and analyze their independent value as predictors of RV dysfunction. Methods and Results: We examined 76 consecutive patients with biopsy-proven AL amyloidosis. Each patient received complete clinical evaluation, troponin I, NT-proBNP assay and comprehensive echocardiographic evaluation. Considering a tricuspidal annulus plane systolic excursion (TAPSE) value

Original languageEnglish
Pages (from-to)97-102
Number of pages6
JournalAmyloid
Volume21
Issue number2
DOIs
Publication statusPublished - 2014

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Keywords

  • AL amyloidosis
  • NT-proBNP
  • Right ventricular dysfunction
  • Troponin

ASJC Scopus subject areas

  • Internal Medicine
  • Medicine(all)

Cite this

Cappelli, F., Baldasseroni, S., Bergesio, F., Padeletti, L., Attanà, P., Pignone, A. M., Grifoni, E., Ciuti, G., Fabbri, A., Tarantini, F., Marchionni, N., Gensini, G. F., & Perfetto, F. (2014). Biohumoral markers as predictor of right ventricular dysfunction in AL Amyloidosis. Amyloid, 21(2), 97-102. https://doi.org/10.3109/13506129.2014.884971