Abstract
Two different types of conduits, one biological, obtained with homologous glutaraldehyde preserved vein segments and the other synthetic bioabsorbable, made with Poly [L-lactide-co-6-caprolactone], were evaluated as guides for nerve repair in alternative to autologous grafts in an experimental animal model. Under general anesthetic, the ischiatic nerve of a number Wistar rats was transacted to create a 1 cm gap, which was then repaired by means of the conduits or autologous grafts. Controls were performed at 1, 3 and 6 months; nerve regeneration was effective with both conduits, but the count of myelinated axons showed a significant difference between the synthetic and biological tubes (p
| Original language | English |
|---|---|
| Pages (from-to) | 225-230 |
| Number of pages | 6 |
| Journal | International Journal of Artificial Organs |
| Volume | 18 |
| Issue number | 4 |
| Publication status | Published - 1995 |
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Keywords
- Microsurgery
- Nerve grafts
- Nerve reconstruction
- Nerve regeneration
- Polylactic acid
- Preserved vein
ASJC Scopus subject areas
- Biophysics
Cite this
Biological and synthetic conduits in peripheral nerve repair : A comparative experimental study. / Giardino, R.; Aldini, N. N.; Perego, G.; Cella, G.; Maltarello, M. C.; Fini, M.; Rocca, M.; Giavaresi, G.
In: International Journal of Artificial Organs, Vol. 18, No. 4, 1995, p. 225-230.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Biological and synthetic conduits in peripheral nerve repair
T2 - A comparative experimental study
AU - Giardino, R.
AU - Aldini, N. N.
AU - Perego, G.
AU - Cella, G.
AU - Maltarello, M. C.
AU - Fini, M.
AU - Rocca, M.
AU - Giavaresi, G.
PY - 1995
Y1 - 1995
N2 - Two different types of conduits, one biological, obtained with homologous glutaraldehyde preserved vein segments and the other synthetic bioabsorbable, made with Poly [L-lactide-co-6-caprolactone], were evaluated as guides for nerve repair in alternative to autologous grafts in an experimental animal model. Under general anesthetic, the ischiatic nerve of a number Wistar rats was transacted to create a 1 cm gap, which was then repaired by means of the conduits or autologous grafts. Controls were performed at 1, 3 and 6 months; nerve regeneration was effective with both conduits, but the count of myelinated axons showed a significant difference between the synthetic and biological tubes (p
AB - Two different types of conduits, one biological, obtained with homologous glutaraldehyde preserved vein segments and the other synthetic bioabsorbable, made with Poly [L-lactide-co-6-caprolactone], were evaluated as guides for nerve repair in alternative to autologous grafts in an experimental animal model. Under general anesthetic, the ischiatic nerve of a number Wistar rats was transacted to create a 1 cm gap, which was then repaired by means of the conduits or autologous grafts. Controls were performed at 1, 3 and 6 months; nerve regeneration was effective with both conduits, but the count of myelinated axons showed a significant difference between the synthetic and biological tubes (p
KW - Microsurgery
KW - Nerve grafts
KW - Nerve reconstruction
KW - Nerve regeneration
KW - Polylactic acid
KW - Preserved vein
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UR - http://www.scopus.com/inward/citedby.url?scp=0029010015&partnerID=8YFLogxK
M3 - Article
C2 - 8530203
AN - SCOPUS:0029010015
VL - 18
SP - 225
EP - 230
JO - International Journal of Artificial Organs
JF - International Journal of Artificial Organs
SN - 0391-3988
IS - 4
ER -