Abstract
Two different types of conduits, one biological, obtained with homologous glutaraldehyde preserved vein segments and the other synthetic bioabsorbable, made with Poly [L-lactide-co-6-caprolactone], were evaluated as guides for nerve repair in alternative to autologous grafts in an experimental animal model. Under general anesthetic, the ischiatic nerve of a number Wistar rats was transacted to create a 1 cm gap, which was then repaired by means of the conduits or autologous grafts. Controls were performed at 1, 3 and 6 months; nerve regeneration was effective with both conduits, but the count of myelinated axons showed a significant difference between the synthetic and biological tubes (p
| Original language | English |
|---|---|
| Pages (from-to) | 225-230 |
| Number of pages | 6 |
| Journal | International Journal of Artificial Organs |
| Volume | 18 |
| Issue number | 4 |
| Publication status | Published - 1995 |
Keywords
- Microsurgery
- Nerve grafts
- Nerve reconstruction
- Nerve regeneration
- Polylactic acid
- Preserved vein
ASJC Scopus subject areas
- Biophysics
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Giardino, R., Aldini, N. N., Perego, G., Cella, G., Maltarello, M. C., Fini, M., Rocca, M., & Giavaresi, G. (1995). Biological and synthetic conduits in peripheral nerve repair: A comparative experimental study. International Journal of Artificial Organs, 18(4), 225-230.