Biological effects of a neurotoxic pesticide at low concentrations on sea urchin early development. A terathogenic assay

A. Morale, L. Coniglio, C. Angelini, G. Cimoli, A. Bolla, D. Alleteo, P. Russo, C. Falugi

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Dose-dependent terathogenic effects of an organophosphate insecticide were found during early sea urchin development. This biological assay is low cost, easy to measure, and allows to detect the effects of the exposure of organisms to the active principle at concentrations lower than the acceptable daily intake (ADI) for man. Effects were found independently from the stage of exposure, and were major as earlier exposure occurred. The stronger effects were exerted on the elongation of the skeletal rods, that was easily measured by following the migration of primary mesenchyme cells, labelled by WGA (wheat germ agglutinin).

Original languageEnglish
Pages (from-to)3001-3010
Number of pages10
JournalChemosphere
Volume37
Issue number14-15
DOIs
Publication statusPublished - Dec 1998

Fingerprint

No-Observed-Adverse-Effect Level
Insecticides
Wheat Germ Agglutinins
Organophosphates
Sea Urchins
Mesoderm
Pesticides
Biological Assay
Elongation
Assays
pesticide
assay
Costs and Cost Analysis
Costs
organophosphate
insecticide
wheat
effect
biological effect
sea

ASJC Scopus subject areas

  • Environmental Chemistry
  • Environmental Science(all)

Cite this

Morale, A., Coniglio, L., Angelini, C., Cimoli, G., Bolla, A., Alleteo, D., ... Falugi, C. (1998). Biological effects of a neurotoxic pesticide at low concentrations on sea urchin early development. A terathogenic assay. Chemosphere, 37(14-15), 3001-3010. https://doi.org/10.1016/S0045-6535(98)00341-5

Biological effects of a neurotoxic pesticide at low concentrations on sea urchin early development. A terathogenic assay. / Morale, A.; Coniglio, L.; Angelini, C.; Cimoli, G.; Bolla, A.; Alleteo, D.; Russo, P.; Falugi, C.

In: Chemosphere, Vol. 37, No. 14-15, 12.1998, p. 3001-3010.

Research output: Contribution to journalArticle

Morale, A, Coniglio, L, Angelini, C, Cimoli, G, Bolla, A, Alleteo, D, Russo, P & Falugi, C 1998, 'Biological effects of a neurotoxic pesticide at low concentrations on sea urchin early development. A terathogenic assay', Chemosphere, vol. 37, no. 14-15, pp. 3001-3010. https://doi.org/10.1016/S0045-6535(98)00341-5
Morale, A. ; Coniglio, L. ; Angelini, C. ; Cimoli, G. ; Bolla, A. ; Alleteo, D. ; Russo, P. ; Falugi, C. / Biological effects of a neurotoxic pesticide at low concentrations on sea urchin early development. A terathogenic assay. In: Chemosphere. 1998 ; Vol. 37, No. 14-15. pp. 3001-3010.
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